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Flashcards in Psychotic disorders Deck (35):
1

What are the neural bases for psychotic disorders?

reduced regional brain volume, enlarged cerebral ventricles, reduced limbic regions, dopamine function

2

What are some of the identified risk factors for schizophrenia?

low SE status, low IQ, perinatal factors, cannabis use

3

Distinguish positive versus negative symptoms of schizophrenia

positive - hallucinations,
negative - lack of motivation, poor self care, alogia, asociality

4

What are the medications used to treat schizophrenia?

antipsychotics, psychosocial support

5

What is schizoaffective disorder and how is it different from schizophrenia?

have symptoms of schizophrenia plus major mood disturbance. psychotic features persist 2 weeks after mood symptoms resolve

6

What is the treatment for schizoaffective disorder?

antipsychotics plus mood stabilizers

7

What is schizophreniform disorder?

schizophrenia that lasts 6 months and does not involve social withdrawal

8

What is delusional disorder?

non-bizarre delusions without psychotic symptoms, typically long term and non-remitting

9

What populations seem to be at risk for delusional disorder?

women, migratory patterns, paranoid

10

What are the treatments for delusional disorder?

psychotherapy

11

What is the definition of a brief psychotic episode?

psychotic symptoms lasting 1 day to 1 month

12

When can brief psychotic episodes occur?

post partum, post stressor

13

What medical conditions should be considered for psychosis?

CNS disease, Addison's/Cushings, B12/folate,

14

What are the DSM IV criteria for schizophrenia?

2 or more for at least 1 month:
- delusions
- hallucinations
- disorganized speech
- catatonia
- negative symtpoms
Only 1 required if delusions are a running voice
Duration of symptoms more than 6 months not allowed

15

What are the different types of schizophrenia?

Paranoid, disorganized (disorganized speech, poor functioning, early onset) catatonic (rare, echolalia and echopraxia present) residual (prominent negative symptoms)

16

Describe epidemiology for schizophrenia

More common among those born in winter, men at 20, women at 30
Post psychotic depression
Substance abuse common
Very strong genetic predisposition

17

What is folie a deux?

Shared psychotic disorder when patient develops same delusional symptoms

18

What medications are especially helpful in the treatment of negative symptoms of schizophrenia?

clozapine, olanzepine

19

What medications can increase schizophrenia medication compliance?

injectable haloperidol

20

What medication can be useful in treating tardive dyskinesia?

clozapine

21

What is the rate of suicide in schizophrenics?

10%

22

What drugs can induce a psychotic event?

amphetamines

23

How does schizophrenia differ in males vs. females?

incidence is the same - occurs at earlier age in men; worse prognosis in men

24

A patient with schizophrenia presents with hyponatremia - what is the cause?

psycogenic polydipsia

25

A man becomes agitated after a period of brooding. this is called...

amok

26

A man becomes convinced that his penis is receding into his body. This is called..

koro

27

A Brazilian lady presents with depressive and anxiety symptoms. This is..

nervios

28

An Indian man presents with weakness, anxiety and is preoccupied by semen discharge. This is..

Dhat

29

A Native American man presents with a preoccupation with death. This would be called..

ghost sickness

30

What symptom is most specifc for schizophrenia?

bizarre delusions

31

What is the lifetime risk of suicide in schizophrenics?

10%

32

What are the soft neurological signs associated with schizophrenia?

Sensory gating issues, decreased ability to habituate to repeated stimuli

33

What is palinopsia?

Sense of object remaining even after stimulus removed

34

What is one of the advantages of aripiprazole compared to other atypcal antipsychotics?

less likely to cause weight gain

35

What is the neurological correlate of schizophrenia?

lateral ventricular enlargement