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Flashcards in Mood Disorder Deck (39):
1

What are the SIGECAPS criteria for depression?

sleep, insomnia, guilt, energy, concentration, appetite, psychomotor, suicidiality

2

What are the criteria for dysthymia?

2 years of chronically depressed mood most of the time

3

What are the criteria for depression?

5 of criteria

4

What is the definition of bipolar I disorder?

one occurance of mania (only requirement), often periods of depression in between

5

What is the recommended treatment for bipolar disorder?

antipsychotics, benzos, mood stabilizer, ECT during manic episodes

6

What are the symptoms of mania?

distractibility, irritability, grandiosity, flight of ideas, activity, speech, thoughtlessness

7

What is a mixed episode?

criteria for both manic and major depressive episode met

8

What is the difference between mania and hypomania?

mania - lasts 7 days vs. hypomania 4 days
no major impairment in functioning, no psychotic features

9

What are the most common sleep problems associated with MDD?

difficulty falling asleep, early morning awakening

10

What is the etiology of MDD?

neurotransmitter deficiencies, high cortisol, abnormal thyroid axis, psychosocial events, genetics

11

What proporotion of patients show a response to antidepressants?

50-60%

12

What are the characteristics of an atypical depression?

hypersomnia, hyperphagia, reactive mood, reactivity to rejection

13

What is the definition of rapid cycling?

4 or more episodes in 1 year

14

What is the typical course of mania? How often do they reoccur?

3 months, 90% of time reoccur within 5 years

15

What are some of the prominent side effects of lithium?

weight gain, tremor, GI upset, polyruria

16

What are the major types of depression?

melancholy, atypical, catatonia, psychotic

17

What is the definition of bipolar II disorder?

one or more depressive episodes with at least 1 hypomania

18

What are the symptoms of dysthymic disorder? How do you distinguish it from depression?

critieria: concentration, hopelessness, appetite, insomnia, low energy, self esteem issues
depression for more than 2 years, 2 critiera, never asymptomatic for more than 2 months
NOTE: never have psychotic symptoms

19

What is cyclothymic disorder?

alternating periods of hypomania with mild/moderate depressive symptoms

20

What are the criteria for seasonal affective disorder?

2 consecutive years of major depressive episodes during same season

21

What are the criteria for postpartum depression?

onset within 4 weeks

22

What are the criteria for adjustment disorder?

symptoms within 3 months of event that impair functioning - symptoms resolve within 6 months

23

What is the most effective treatment for depression with psychotic features?

ECT

24

What percentage of concordance is there between monozygotic twins and depression?

70

25

How often does depression occur in stroke patients?

30-50% of the time

26

How frequently does postpartum depression occur?

10-15% of mothers

27

How long does the risk of post-stroke depression last?

up to 2 years

28

What is the lifetime risk of suicide in mood disorders?

10-15%

29

Women on antidepressants are at risk for...

depression

30

What is the strongest indication for ECt?

treatment resistant depression with recurrent suicidal ideation

31

What are the contraindications to ECT?

no heart attack in last 3 months, no increase in ICP (no mass lesion)

32

How many treatments of ECT may be necessary to have an effect in refractory depression?

10

33

What is the best medication prescription for someone with depression with psychotic features?

SSRI and antipsychotic

34

What is the best medication treatment for mania?

Valproate acid or lithium

35

What is the best medication to prescribe to an individual in mania acutely?

Antipsychotic and benzo

36

What percentage of people in major depression respond without therapy?

1/3

37

What are the criteria for bereavement?

Symptoms not too debilitating within 2 months of truama

38

What symptoms change first with antidepressent therapy?

Sleep symptoms

39

What part of the brain is responsible for serotonin release?

Raphe nuclei