Adrenergic Agonists

Question 1

Epinephrine

Answer 1

• Nonselective
• Indications:
  
  • IM/SubQ: allergic reaction (anaphylaxis)
  • IV: cardiogenic shock (cardiac arrest)
  • Aerosol: airway obstruction (bronchospasm)
• Very high risk for extravasation (antidote: phentolamine mesylate)
• Side effects: HTN, tachycardia, worsening prostate disease, mydriasis, hypercoaguability, lowers GI motility & secretions, blood shunting, glycogenolysis, NS changes/mental status changes (if crosses BBB)