Adrenergic Agonists and Antagonists II Flashcards Preview

CV II Exam 3 > Adrenergic Agonists and Antagonists II > Flashcards

Flashcards in Adrenergic Agonists and Antagonists II Deck (42)
Loading flashcards...
1

cardiogenic shock

with compromised kidney function

dopamine

2

fenoldopam

D1 selective agonist
-IV infusion for severe HTN

3

dobutamine

given as racemic mix

4

prazosin

alpha1selective blocker
-short half life

5

propranolol

non-selective beta blocker

6

emergency to stimulate heart rate in bradycardia or heart block

-before placement of pacemaker or patients with torsades de points

isoproterenol

7

short term treatment of cardiac decompensation after cardiac surgery or pt with CHF or acute MI

dobutamine

8

clonidine

alpha2 agonist

central acting

9

methyldopa

alpha2 agonist
-for pregnant women

central acting

10

tamsulosin

alpha1a selective antagonist -for BPH

11

carvedilol

non-selective beta blocker

also antioxidant and block Ca entry

12

carteolol

non-selective beta blocker - and agonist at beta2 as well as activate NO production

13

atenolol

beta1 selective antagonist

14

metoprolol

beta1 selective antagonist

15

esmolol

beta1 selective antagonist

short acting - only during surgery

16

labetalol

alpha and beta blocker

17

carvedilol

alpha and beta blocker

18

3rd generation beta blockers

have mechanisms for vasodilation

calcium block, NO production, beta2 agonist activity, antioxidant

19

patient with HTN and bronchospasm, DM, PVD, or raynauds

use beta1 selective antagonist

20

beta antagonists

stronger effects when sympathetic activity is tonically increased
-ex/ exercise

21

beta blockers

slow conduction in atria and AV node
-increased refractory period of AV node

reduced work of heart and O2 consumption

22

labetalol and carvedilol

beta blockers AND alpha1 blockers

CO maintained with large fall in peripheral resistance

23

beta blockers as antihypertensives

don't decrease BP in normal patients
-but pt with HTN - do decreased BP

24

renin release

beta1 - blocked by beta antagonists

25

pindolol

no effect on plasma renin activity

26

exacerbation of HF in patients with HF, acute MI, or cardiomegaly

with beta blocker use

27

prolonged life in HF patients

chronic beta-blockers

28

verapamil and beta blockers

may lead to AV conduction defects

29

abrupt discontinuation of beta blockers

exacerbate angina
-increase risk of sudden death

bc of upregulation of beta receptors

30

decreased exercise tolerance

with beta blockers