Flashcards in Alcohol Related Disease Deck (19):
What does alcohol cause in the liver causing direct toxicity?
What can alcohol cause in the alimentary system?
Spontaneous bacterial peritonitis
What is hepatic encephalopathy?
Permanent brain dysfunction as a result of liver failure
What are the causes of hepatic encephalopathy?
What are the signs of advanced liver disease?
Loss of axillary and pubic hair
What lab investigations would be done to diagnose liver disease?
AAT and ALT
Gamma Glutamyl Transferase (GGT)
What is the treatment of hepatic encephalopathy?
Bowel clear out - lactulose or enema
Antibiotics for any underlying infection
Supportive care - ITU, airway support, nasogastric tube
What are the signs and symptoms of spontaneous bacterial peritonitis?
Signs of sepsis - tachycardia, fever
What investigations would be done if suspecting spontaneous bacterial peritonitis?
Fluid protein and glucose levels
White cell content
What is the treatment for spontaneous bacterial peritonitis?
Ascetic fluid drainage
IV albumin infusion
What is the typical presentation of alcoholic hepatitis?
Decompensated liver function - low albumin, raised prothrombin time
What investigations would be done if suspecting alcoholic hepatitis?
What is the treatment of alcoholic hepatitis?
Treat infection and encephalopathy
Treat alcohol withdrawal
Protect against GI bleeding
Treat any renal damage
Steroids if severe grading on Glasgow Alcoholic Hepatitis score
What is fatty liver disease related to?
What is steatohepatitis?
Fat and inflammation in the liver
The histology of steatohepatitis will be similar to the histology of what other condition?
Alcohol induced liver damage
What proportion of patients with fatty liver disease will progress to cirrhosis?
What investigations would be done if suspecting fatty liver disease?