Allergies and Immunologic Disease

Question 1

A common oral lesions involving fungiform or filiform papilla are called what?

Answer 1

Transient Lingual Papillitis

Question 2

What are the 3 patterns of Transient Lingual Papillitis?

Answer 2

1-Localized
2-Generalized
3-Diffuse, papulokeratotic variant (like a callus version)

Question 3

What is Recurrent Aphthous Ulcerations (RAU) also known as?

Answer 3

Recurrent aphthous stomatitis

Question 4

In a normal patient, where do Recurrent Apthous ulcers occur?

Answer 4

Movable mucosa

Question 5

What are the 3 clinical variations of Recurrent Apthous ulcers?

Answer 5

1-Minor (85%)
2-Major (10%)
3-Herpetiform (5%)

Question 6

Which variation of Recurrent Apthous ulcers occurs in childhood on moveable mucosa and are 3-10 mm in size?

Answer 6

Minor

*heal in 7-14 days, no scarring, fewest recurrences

Question 7

Which variation of Recurrent Apthous ulcers occurs in adolescents, are associated with suttons disease, and are 1-3 cm?

Answer 7

Major

*heal in 2-6 wks, possible scarring

Question 8

Which variation of Recurrent Apthous ulcers occurs in adults, have up to 100 ulcerations, and are 1-3 mm mainly on moveable mucosa?

Answer 8

Hepetiform

*heal in 7-10 days, no scarring, most frequent recurrence

Question 9

What is typically prescribed for recurrent aphthous ulcers?

Answer 9

topical corticosteroid (clobetasol proprionate)

Question 10

Ocular inflammation, genital ulcers and skin lesions typically in Turkish, Japanese or eastern mediterraneans is called what?

Answer 10

Behcet’s Syndrome

*joint pain is also a common complaint

Question 11

Which Multisystem granulomatous disorder of unknown cause happens more often in African americans, typically have an abnormal chest x-ray with skin lesions?

Answer 11

Sarcoidosis

*Involve lungs, lymph nodes, skin, eyes, salivary glands

Question 12

What are the two types of skin lesions involved with sacradosis?

Answer 12

1-Lupus pernio (Chronic, purple, indurated lesions on H&N)
2-Erythema nodosum (Scattered, nonspecific, tender, red nodules on lower legs)

Question 13

What are two different syndromes associated with sarcoidosis?

Answer 13

1-Lofgren’s syndrome

2-Heerfordt’s syndrome

Question 14

What 3 things make up Lofgren’s syndrome?

Answer 14

1-Erythema nodosum
2-Bilateral hilar lymphadenopathy
3-Arthralgia

Question 15

What 4 things make up Heerfordt’s syndrome?

Answer 15

1-Parotid enlargement
2-Inflammation of eye
3-Facial paralysis
4-Fever

Question 16

What 3 things are used to diagnose Sarcoidosis?

Answer 16

1-Elevated serum angiotensin-converting enzyme levels
2-Chest XRAY
3-Kveim test – no longer used

Question 17

What condition most commonly involves the lips as non-tender persistent swelling?

Answer 17

Orofacial Granulomatosis

Question 18

What 3 things make up Melkersson-Rosenthal syndrome?

Answer 18

1-Cheilitis granulomatosa (swollen lip)
2-Facial paralysis
3-Fissured tongue

Question 19

What 3 things are typical of classic Wegener’s granulomatosis?

Answer 19

1-Necrotizing granulomatous lesions of respiratory tract
2-necrotizing glomerulonephritis
3-systemic vasculitis of small arteries and veins

Question 20

What oral lesion is a characteristic manifestation of Wegener’s Syndrome?

Answer 20

Strawberry gingivitis

Question 21

How is Wegner’s Syndrome diagnosed?

Answer 21

Indirect immunofluorescence detects presence of antineutrophil cytoplasm antibodies (ANCA)

Question 22

Which two types of Antineutrophil Cytoplasm Antibodies are detected for when diagnosing Wegener’s syndrome?

Answer 22

1-Perinuclear (p-ANCA)

2-Cytoplasmic (c-ANCA) (most useful)

Question 23

Large, red gingiva that may superficially slough due to flavoring is most likely what?

Answer 23

Contact Stomatitis from Cinnamon

Question 24

AKA Quincke’s disease, what condition is diffuse edematous swelling of the soft tissues with no pain, but itching and erythema may be present?

Answer 24

Angioedema

*Most commonly caused by histamine release from mast cell degranulation

Question 25

Angioedema with diffuse involvement of the head and neck is likely caused by what?

Answer 25

Angiotensin-converting enzyme (ACE) inhibitors such as the “prils” for Hypertension