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Oral Pathology > Soft Tissue Tumors > Flashcards

Soft Tissue Tumors Flashcards

1
Q

What is the most common “tumor”/neoplasm of the oral cavity associated with trauma?

A

Fibroma

*Reactive hyperplasia of fibrous connective tissue in response to local irritation or trauma

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2
Q

What is the most common location for a Fibroma?

A

Buccal mucosa along bite line

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3
Q

Fibrous tumor with distinctive features; not associated with chronic irritation are called what?

A

Giant Cell Fibroma

*usually in younger patient on Gingiva

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4
Q

Typically bilateral, what lesion is similar microscopically to Giant Cell fibroma and found in 99% of children?

A

Retrocuspid Papilla

*Lungual to mandibular cuspids

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5
Q

A Tumor-like hyperplasia of fibrous connective tissue as part of a the inflammatory process, usually on the facial aspect of the alveolar ridge is called?

A

Inflammatory Fibrous Hyperplasia (IFH)

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6
Q

Inflammatory Fibrous Hyperplasia that is in association with the flange of an ill-fitting denture is called what?

A

Epulis Fissuratum

*Clinical diagnosis

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7
Q

Small, erythematous pebbly reactive tissue growth under a denture (usually maxillary) is called?

A

Inflammatory Papillary Hyperplasia (IPH)

*Ill-fitting or lack of denture hygiene

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8
Q

Most commonly on the buccal mucosa in the oral cavity, a true neoplasm exhibiting fibroblastic and histiocytic differentiation is called?

A

Fibrous Histiocytoma

*dermatofibroma when it is on the skin

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9
Q

What results from overproduction of hyaluronic acid by fibroblasts?

A

Oral Focal Mucinosis

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10
Q

What are the 3 P’s and an F of a differential diagnosis for “bump on the gums”?

A

1-Fibroma
2-Pyogenic granuloma
3-Peripheral Ossifying Fibroma
4-Peripheral Giant Cell Granuloma

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11
Q

What fiery red lesion is not a true granuloma and is a reaction to local irritation?

A

Pyogenic Granuloma

*may grow quickly. Excise down to the periosteum

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12
Q

Where are Pyogenic Granulomas found?

A

Gingiva (75%), followed by lips, tongue and buccal mucosa

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13
Q

What is a pyogenic tumor called if a pregnant woman has one?

A

Granuloma Gravidarum or Pregnancy tumor

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14
Q

A reactive lesion caused by local irritation or trauma that occurs exclusively on the gingiva or edentulous alveolar ridge with cupping resorption of bone is called?

A

Peripheral Giant Cell Granuloma (PGCG)

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15
Q

Which lesion occurs exclusively on the gingiva, is a pale color
, and appears as a nodular mass that usually originating from the dental papilla?

A

Peripheral Ossifying Fibroma (POF)

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16
Q

By far the most common mesenchymal neoplasm, what yellow/mucosal colored lesion is a benign tumor of fat?

A

Lipoma

*floats in formalin

17
Q

Pain with peripheral numbness around most commonly in the mental foramen area is likely what?

A

A neuroma

18
Q

What are the two kinds of Neuromas?

A
  • Traumatic neuroma

- Palisaded encapsulated neuroma (PEN)

19
Q

What is another name for a Palisaded encapsulated neuroma?

A

Solitary circumscribed neuroma

20
Q

A benign neural neoplasm of Schwann cell origin is called what?

A

Schwannoma (Neurilemoma)

*up to half are in the Head and Neck, most on tongue

21
Q

What are the two Histopathologic features of a Schwannoma?

A

1-Antoni A (Spindle shaped schwann cells forming a palisaded arrangement, eosiniphilic are called Verocay body)
2-Antoni B (no organization)

22
Q

The most common type of peripheral nerve neoplasm, most commonly found on the tongue or buccal mucosa intraorally are called?

A

Neurofibroma

*Patient should be evaluated for neurofibromatosis

23
Q

AKA von Recklinghausen’s disease of the skin, which of the 8 recognized forms of Neurofibromatosis is most common?

A

Neurofibromatosis Type 1 (NF1)

*Feels like a bag of worms

24
Q

What are 4 important diagnostic criteria for Neurofibromatosis?

A

1- 6 or more Cafe au lait macules (Coast of California)
2-Two or more NF
3-Frecking of axillary region (Crowe’s sign)
4-Two or more iris hamartomas (lisch nodules)

25
Q

What are 3 oral manifestations found in 90% of NF1 patients?

A

1-Enlargement of fungiform papilla (50%)
2-Intraoral neurofibromas (25%)
3-Enlargement of the mandibular foramen or canal

26
Q

What condition is characterized by adrenal gland tumors (pheochromocytoma), thyroid tumors (medullary carcinoma) mucosal neuromas (with a predilection for the oral cavity) and marfanoid (alien like) elongated face and limbs?

A

Multiple Endocrine Neoplasia, Type 2B (MEN 2B)

*Often have large lips due to neuromas and Bilateral neuromas of the commissural mucosa

27
Q

____% of Multiple Endocrine Neoplasia, Type 2B develop pheochromocytoma and ______% develop medullary carcinoma of the thyroid gland

A

50, 90

28
Q

A rare pigmented tumor, usually occuring during the 1st year of life with a
striking predilection for anterior maxilla is likely what?

A

Melanotic neuroectodermal tumor of infancy

*Clinically black/blue. High urinary Vanillylmandelic acid

29
Q

Which benign soft tissue neoplasm had a predilection for the oral cavity, is yellow/mucosal colored, is usually on the dorsal tongue and exhibit pseudoepitheliomatous hyperplasia (PEH)?

A

Granular Cell tumor

*S-100 positive

30
Q

What lesion occurs almost exclusively on the alveolar ridges of newborns in the incisor-canine region and does NOT cause Pseudoepitheliomatous hyperplasia (PEH)?

A

Congenital Epulis

*S-100 negative. Most common on Maxillary ridge

31
Q

What is the most common tumor of infancy and is a tumor of blood vessels?

A

Hemangioma

*Clinically blanch

32
Q

Which rare, nonhereditary developmental condition is characterized as having port wine stain or nevus flammeus in associated with trigeminal nerve and is associated with convulsive disorders?

A

Sturge-Weber Angiomatosis

*Likely have gingival hyperplasia due to convulsive medications

33
Q

Often appearing like frog eggs or tapioca pudding, a benign tumor of lymphatic vessels is called what?

A

Lymphangioma

*may cause macroglossia

34
Q

Benign tumors of smooth muscle are called?

A

Leiomyoma

35
Q

Benign neoplasm of skeletal muscle are called?

A

Rhabdomyoma

*Extracardiac rhabdomyomas are very rare but have a predilection for the H&N

36
Q

The name of a malignant soft tissue cancer ends in?

A

Sarcoma

37
Q

What condition is caused by HHV-8, is classically in Italian, Jewish, or Slavic?

A

Kaposi’s Sarcoma

38
Q

What are the 4 clinical presentations of Kaposi’s Sarcoma?

A

1-Classic
2-Endemic (African)
3-Iatrogenic immunosuppression associated
4-AIDS related

39
Q

A Malignancy of skeletal muscles is called?

A

Rhabdomyosarcoma

Oral Pathology (18 decks)

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