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Dermatology week 1 > Allergy and Skin > Flashcards

Flashcards in Allergy and Skin Deck (18)
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1

Define hypersensitivity

Immune responses that cause collateral damage to self

2

What mediates type 1 hypersensitivity

IgE

3

What mediates type 2 hypersensitivity

IgG

4

What mediates type 3 hypersensitivity

Immune mediated complex

5

What mediates type 4 hypersensitivity

T Cell mediated

6

What is animal dander

Animal sheddings

7

What 4 things do mast cells produce in a hypersensitivity reaction

Histamines
Leukotrienes
Cytokines
Prostoglandins

8

What is urticaria

Itchy lesions that appear within the hour of contact with allergen

9

Angioedema

Localized swelling of the subcutaneous tissue or mucous membrane

10

Give 4 tests that can be done to test for an allergy

RAST test
Skin prick test
Challenge testing
Serum mast cell tryptase level

11

When do you use challenge testing

If skin prick test is negative

12

What treatment prevents the effects of mast cell activation

Anti-histamines

13

What treatment is an anti-inflammatory

Cortiosteroids

14

What treatment blocks mast cell activation

Sodium cromoglycate

15

What is the dose for adults and what is the dose for children with adrenaline

300 micrograms
150 micrograms

16

Describe type 4 hypersensitivities

Delayed hypersensitivity, T cell mediated and symptoms usually appear after 1/2 days

17

What is the gold standard test for allergic contact dermatitis

Patch testing

18

Is irritant contact dermatitis immune or non-immune mediated

Non-immune mediated