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Dermatology week 1 > Basic Skin Immunology > Flashcards

Flashcards in Basic Skin Immunology Deck (10)
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1

What T cells are mainly found in the epidermis

CD8+ t cells

2

What Th cell is associated with psoriasis

Th1

3

What Th cell is associated with atopic dermatitis

Th2

4

What Th cell is associated with psoriasis and atopic dermatitis

Th17

5

Where are T cells produced and sensitized

Produced in bone marrow and sensitized in the thymus

6

Information on class 1 MHC

Found on almost all cells, presents antigen to cytotoxic T cells and presents endogenous antigens

7

Information on class 2 MHC

Found on antigen presenting cells (B cells and macrophages), present to Th cells and present exogenous antigens

8

Triggers for psoriasis

Bacterial pharyngitis, HIV and stress

9

Drugs that trigger psoriasis

Beta blockers and lithium

10

What hypersensitivities lead to an arthus reaction

Type 3 hypersensitivity