Flashcards in Allergy drugs Deck (14):
1st gen antihistamines?
can cross BBB leading to CNS effects
dizziness, sedation, etc
2nd gen antihistamines?
loratadine/ desloratadine (claritin/clarinex)
Lower anticholinergic effects
rebound nasal congestion from use of alpha-adrenergic agonists delivered in aerosol form
- have rapid onset and few systemic effects but should not be used long term because of rebound
- educate pt. not to use long-term
-may prescribe nasal steriods while weening off.
inhalation; nebulizer; oral
idications: COPD and nasal dischage
Contraindications: HS to atropine or ipratropiib bromide
AE: glacoma (narrow angle)
MOA: cholnergic antagonist of ACH.
Drug Interactions: don't mix with morphine or oxymorphine
mast cell stabilizers
indications: allergic rhinitis
AE: bad taste in mouth, bring sensation eye, cough, throat, epistaxis, risk of bronchospasm
MOA: Inhibits mast cell degranulation
Low potency intranasal steroid
Triamcinolone -nasacort AQ,
Mometasone - Nasonex.
Medium potency intranasal steroid
Beclomethasone - Beconase AQ,
Fluisolide - Nasalide
High potency intranasal steroid
Budesonide - Rhinocort
For: anti inflammatory properties reduce nasal obstruction, rhinorrhea, sneeaing and pruritis
AE: epistasix, cataracts, growth velocity changes, HPA axis
Intranasal antihistamines: indications and CI?
Indications: allergic rhinitis, allergic conjunctivis, vasomotor rhinitis
AE: contact dermatitis, headache, somnolence, fatigue
Intranasal antihistamines: MOA and Drug interactions
MOA: selective H1 receptor antagonist that blocks the release of histamine
Drug Ix: fatigue, lack of alertness, avoid alcohol
aspirin with asthma and nasal polyposis
aspirin should be avoided as it may precipitate a severe episode of bronchospasm,
-known as triad asthma
- immunologic salicylate sensitivity
epinephrine (epi pen)
Indications and CI:
Indications: hypersensitivity reactions (anaphylaxis)
CI: no absolute CI in a life threatening situation