alpha glucose inhibitirs (AGI) Flashcards
What is the MOA of AGIs
Lower prabdial hyperglycemia by antagonizing brush boarder enzymes that digest carbs
Name an AGI
Precose
Do AGIs cause hypoglycemia?
No (like metformin and AGIs)
How to you take AGIs?
With first bite of meal
Who can’t take AGIs?
IBD patients, intestinal obstruction
gLP-1 agonist is what?
Byetta
Name a DDP IV inhibitor
Januvia
What is the significance of these medications
They are glucose defendant so if you don’t eat they won’t cause hypoglycemia they will just work less
What is the AE of byetta?
Pancreatitis
What is the role of Amylin?
Secreted with insulin it delays gastric emptying and increases satiety and regulated post prabdial glucagon
Which medication is a Amylin analogue?
Symilin