Alpha-glucosidase Inhibitors

Question 1

MOA of alpha-glucosidase inhibitors

Answer 1

Inhibit enzymes that break down carbs
Decrease glucose absorption in the intestines

Question 2

Alpha-glucosidase inhibitors expected change in A1c

Answer 2

Low

Question 3

How are alpha-glucosidase inhibitors administered?

Answer 3

Orally

Question 4

Alpha-glucosidase inhibitors ADEs

Answer 4

GI upset
(ABD pain, diarrhea, flatulence)

Question 5

Alpha-glucosidase inhibitors risk of hypoglycemia

Answer 5

Low

Question 6

Alpha-glucosidase inhibitors impact on weight

Answer 6

Neutral

Question 7

Alpha-glucosidase inhibitors CV impact

Answer 7

Unknown

Question 8

Alpha-glucosidase inhibitors renal impact

Answer 8

Unknown

Question 9

Alpha-glucosidase inhibitors precautions/CIs

Answer 9

Renal dysfunction
IBD, colonic ulceration, intestinal obstruction

Question 10

Alpha-glucosidase inhibitors drug interactions

Answer 10

DIgoxin

Question 11

Alpha-glucosidase inhibitors cost

Answer 11

Low

Question 12

Alpha-glucosidase inhibitors should be taken before, with, or after meals?

Answer 12

Before