Twincretins Flashcards

1
Q

Twincretins are more formally known as

A

GLP-1 and GIP receptor agonists

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2
Q

Twincretins MOA

A

Activates GLP-1 and GIP receptors
Increases insulin release in response to meals

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3
Q

Twincretins expected change in A1c

A

High

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4
Q

Twincretins dosing frequency

A

Weekly

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5
Q

Twincretins route of administration

A

Subcutaneous

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6
Q

Twincretins ADEs

A

GI (NVD)

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7
Q

Twincretins risk of hypoglycemia

A

Low

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8
Q

Twincretins impact on weight

A

Significant loss

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9
Q

Twincretins CV impact

A

Unknown

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10
Q

Twincretins renal impact

A

Unknown

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11
Q

Twincretins precautions/CIs

A

Avoid in medullary thyroid cancer and multiple endocrine neoplasia syndrome type 2 (MEN2)

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12
Q

Twincretins drug interactions

A

May delay oral contraceptive absorption

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13
Q

Twincretin use requires a baseline _______________ and ________________

A

Eye exam
Regular monitoring

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14
Q

Twincretins affect

A

Post-prandial blood sugar

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15
Q

Twincretins administration vehicle

A

Autoinjector

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16
Q

Twincretins require a ______________ to reduce risk of ____________ side effects

A

Long titration
GI