amino acids Flashcards
(37 cards)
how many standard amino acids are there?
20
what is the structure of an amino acid?
a-carbon is bonded to a carboxyl, amino, hydrogen atom and R group
what do amino acids vary by?
the R group, side chain
why is Proline an exception to the structure?
its side chain is attached to the central atom and amino group
describe the structure of hydrophobic amino acids?
uncharged nonpolar side chains. carbon or hydrogen.
what amino acids are hydrophobic?
Glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, tryptophan, proline
what hydrophobic amino acids are aromatic?
phenylalanine and tryptophan
what is the smallest amino acid?
glycine
what is the largest amino acid?
tryptophan
what are the characteristics of hydrophobic amino acids?
Form water-insoluble cores of proteins.
Describe hydrophilic amino acids
uncharged polar side chains. R group no pos or neg charge.
what do hydrophilic amino acids do?
they are on surface of proteins. by interacting with H2O they make proteins soluble.
what hydrophilic amino acids contain a polar hydroxyl group?
Serine, threonine and tryosine
what hydrophilic amino acids contain a highly polar amino functional group?
asparagine and glutamine
what hydrophilic amino acid contains a sulfhydryl group?
Cysteine
what can be added to amino acids with OH in the R chain?
Phosphate
what amino acid can form a disulfide bond ?
Cysteine because it has a sulfhydryl group in the R chain.
what can a sulfhydryl group of 2 molecules do?
it may oxidise spontaneously to form a disulfide compound called cystine
what does disulfide bond between Cys do
stabilises the structure on many proteins
what is an amphoteric molecule?
is a molecule that can act as both an acid and a base.
describe the amino and carboxyl groups at PH7
carboxyl groups deprotonated- neg charge.
carboxyl groups are acidic
amino acids protonated- pos charge
amino groups are basic
acidic amino acids
aspartate or aspartic acid
glutamate or glutamic acid
what are acidic amino acids?
negatively electrically charged
what are the characteristics of acidic amino acids?
carboxyl group dissociates to give H+ and negatively charged carboxyl group at PH7
can H-bond with water
form ionic bonds with basic amino acids