amino acids Flashcards

(37 cards)

1
Q

how many standard amino acids are there?

A

20

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2
Q

what is the structure of an amino acid?

A

a-carbon is bonded to a carboxyl, amino, hydrogen atom and R group

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3
Q

what do amino acids vary by?

A

the R group, side chain

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4
Q

why is Proline an exception to the structure?

A

its side chain is attached to the central atom and amino group

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5
Q

describe the structure of hydrophobic amino acids?

A

uncharged nonpolar side chains. carbon or hydrogen.

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6
Q

what amino acids are hydrophobic?

A

Glycine, alanine, valine, leucine, isoleucine, methionine, phenylalanine, tryptophan, proline

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7
Q

what hydrophobic amino acids are aromatic?

A

phenylalanine and tryptophan

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8
Q

what is the smallest amino acid?

A

glycine

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9
Q

what is the largest amino acid?

A

tryptophan

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10
Q

what are the characteristics of hydrophobic amino acids?

A

Form water-insoluble cores of proteins.

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11
Q

Describe hydrophilic amino acids

A

uncharged polar side chains. R group no pos or neg charge.

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12
Q

what do hydrophilic amino acids do?

A

they are on surface of proteins. by interacting with H2O they make proteins soluble.

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13
Q

what hydrophilic amino acids contain a polar hydroxyl group?

A

Serine, threonine and tryosine

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14
Q

what hydrophilic amino acids contain a highly polar amino functional group?

A

asparagine and glutamine

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15
Q

what hydrophilic amino acid contains a sulfhydryl group?

A

Cysteine

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16
Q

what can be added to amino acids with OH in the R chain?

17
Q

what amino acid can form a disulfide bond ?

A

Cysteine because it has a sulfhydryl group in the R chain.

18
Q

what can a sulfhydryl group of 2 molecules do?

A

it may oxidise spontaneously to form a disulfide compound called cystine

19
Q

what does disulfide bond between Cys do

A

stabilises the structure on many proteins

20
Q

what is an amphoteric molecule?

A

is a molecule that can act as both an acid and a base.

21
Q

describe the amino and carboxyl groups at PH7

A

carboxyl groups deprotonated- neg charge.
carboxyl groups are acidic
amino acids protonated- pos charge
amino groups are basic

22
Q

acidic amino acids

A

aspartate or aspartic acid
glutamate or glutamic acid

23
Q

what are acidic amino acids?

A

negatively electrically charged

24
Q

what are the characteristics of acidic amino acids?

A

carboxyl group dissociates to give H+ and negatively charged carboxyl group at PH7
can H-bond with water
form ionic bonds with basic amino acids

25
basic amino acids
lysine, arginine, histidine
26
what are basic amino acids?
positively charged . basic amino acids associate with H+ to form pos charged groups at PH7
27
how are amino acids linked?
peptide bond
28
does the formation of a peptide bond result in the loss of water
yes
29
is the peptide bond stable
yes
30
what are linked amino acids referred to ?
amino acid residues
31
what is a peptide bond?
a chemical bond formed between carboxyl group of one amino acid and the amino group of the next amino acid
32
what is the direction of the polypeptide chain?
will run from the amino to carboxyl end
33
what is the name of the free amino group at the beginning
the amino terminal or N-terminal
34
what is the free carboxyl group called at the end ?
the carboxyl terminal or C-terminal
35
what does the polypeptide chain consist of ?
a regularly repeating part called the main chain or backbone. variable part comprised of the distinctive side chains.
36
does the chain fold ?
yes, first amino acid could be beside last
37
what does a functional protein consist of ?
one or more polypeptides twisted, folded and coiled into a unique shape