AMNIOTIC FLUID Flashcards

(45 cards)

1
Q

purpose of amniotic fluid examination: (2)

A
  • extent of fetal distress and maturity

- ability of the fetus to survive and early delivery

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2
Q

membranous sac

that surrounds the fetus

A

amnion

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3
Q

functions of amniotic fluid (5)

A
  • cushion
  • fetal movement
  • heat absorber
  • lung development
  • exchange of nutrient
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4
Q

amniotic fluid volume

1st trimester:
3rd trimester:

A
  • 35mL

- 1L

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5
Q

absorption of amniotic fluid water

and solutes into the fetal vascular system

A

intramembranous flow

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6
Q

Excessive accumulation of amniotic fluid

from failure of fetus to swallow

A

polyhydramnios

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7
Q

Decreased amniotic fluid from increased

fetal swallowing

A

oligohydramnios

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8
Q

fetal age can be estimated by measuring _____

give also the values

A

creatinine

<36 weeks 1.5-2.0 mg/dL
>36 weeks >2.0 mg/dL

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9
Q

how to differentiate maternal urine vs amniotic fluid

A

creatinine, urea, glucose, and protein

amniotic fluid:
<3.5 mg/dL
<30 mg/dL
rgt strip + for protein and glucose

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10
Q

specimen collection volume and special consideration

a. 30
b. 40
c. 50
d. 60

A
  • volume: 30 mL
  • discard first 2-3mL because of maternal blood
  • protect the spx from light
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11
Q

this test requires ice and cooled/frozen for up to 72 hrs if needed

A

fetal lung maturity test

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12
Q

these tests require aseptic collection and 37C temp

A

cytogenetic

microbiology

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13
Q

these tests needs centrifuge or filter fluid to remove debris

A

chemical tests

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14
Q

normal color of amniotic fluid

A

colorless with slight to moderate turbidity from cells

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15
Q

blood-streaked amniotic fluid

A

traumatic tap

intra-amniotic hemorrhage

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16
Q

test to differentiate maternal vs fetal blood

A

Kleihauer-Betke test

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17
Q

bright yellow amniotic fluid

A

increased bilirubin

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18
Q

dark green amniotic fluid

A

meconium

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19
Q

dark red brown amniotic fluid

20
Q

this fetal disease is commonly found on Rh (-) pregnant mothers

A

hemolytic disease of the newborn

21
Q

when can HDN happen?

A

second pregnancy

22
Q

which analyte is measured in case of HDN

23
Q

liley graph zone I

A

mildly affected fetus

24
Q

liley graph zone II

A

requires careful monitoring

25
liley graph zone III
severely affected fetus, may require induction of labor
26
marker for neural tube defects
alpha fetoprotein
27
increased levels of AFP may indicate:
anencephaly or spina bifida
28
more specific marker for neural tube defects
acetylcholinesterase
29
common complication of early delivery
respiratory distress syndrome
30
reference method for FLM
lecithin/sphingomyelin ratio
31
primary component of the lung surfactant; increased production after 35th week
lecithin
32
produced at a constant rate after the 26th week to control its counterpart
sphingomyelin
33
L/S ratio required to consider a safe preterm delivery a. 1 b. 2 c. 3 d. 4
> 2.0
34
how is L/S ratio performed?
thin-layer chromatography
35
is an agglutination test using antibody specific for phosphatidyl glycerol that can replace the L/S ratio
amniostat-FLM
36
advantage of amniostat-FLM (2)
- no special equipment needed | - blood and meconium do not interfere with the test
37
this test can be performed at the bedside, amniotic fluid is mixed with 95% ethanol
foam stability
38
a value of >___ indicates FLM a. 45 b. 46 c. 47 d. 48
47
39
Measures the polarization of a fluorescent dye that | binds to surfactant and albumin
microviscosity: fluorescence polarization
40
storage form of lung | surfactants
lamellar bodies
41
which cells secrete lamellar bodies?
type II pneumocytes
42
T or F. lamellar bodies resemble small platelets thus can be counted using platelet analyzers
true
43
T or F. presence of lamellar bodies decreases the OD of the fluid
false
44
lamellar body count that indicates FLM a. >30, 400 b. >25, 400 c. >40, 400 d. >35, 400
>35, 400
45
mg of surfactant required per g of albumin in microviscosity for FLM a. 50 b. 55 c. 60 d. 65
55