Amyloidosis & Pigmentation Flashcards by Jhaunte Braithwaite

Q

What is Amyloidosis?

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Q

What is amyloid?

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Q

Where does amyloid c9me from?

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Q

What is the morphology of amyloid?

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Q

What are the classifications of Amyloidosis?

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Q

Describe systemic Amyloidosis

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Describe localized Amyloidosis

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Describe hereditary Amyloidosis

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Q

Describe the gross appearance of Amyloidosis?

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Q

Describe the microscopic features of Amyloidosis

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What does Amyloidosis look like?

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Q

Describe Amyloidosis of kidney

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Describe Amyloidosis of spleen

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Describe Amyloidosis of the liver

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Q

Describe Amyloidosis of heart

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Q

Discuss the symptoms & pathology of the kidney

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Q

Discuss the symptoms & pathology of the heart Amyloidosis

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Q

Discuss the symptoms & pathology of the liver Amyloidosis

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Q

Discuss the symptoms & pathology of the spleen Amyloidosis

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Q

Discuss the symptoms & pathology of the vascular Amyloidosis

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Q

Discuss the symptoms & pathology of the peripheral nerves Amyloidosis

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Q

Discuss the symptoms & pathology of the coagulation Amyloidosis

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Discuss the symptoms & pathology of the join t Amyloidosis

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Q

What organs are not as commonly affected with Amyloidosis?

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What is the diagnosis of Amyloidosis?

What are the intracellular accumulations?

Contrast endogenous, exogenous accumulations

What are the mechanisms of accumulation ?

What are examples of exogenous pigments?

What is lipofuscin?

What is bile?

What is hemosiderin?

What is the etiology of gout and gouty arthritis?

What is the pathogenesis of gout & gouty arthritis?

What is the epidemiology of gout and gouty arthritis?

What are the risk factors of gout and gouty arthritis ?

What are the classifications of primary and secondary gout?

Describe the morphology of gout

Describe diagnosis of gout

What are the Clinical features of gout?

What are the main endogenous pigments?

What are the main exogenous pigments?

Patient with plasma cell dyscrasias such as multiple myeloma. What type of Amyloid?

AL

Chronic inflammatory conditions like rheumatoid arthritis, chronic osteomyelitis ; bronchiectasis; inflammatory bowel disease. What type of Amyloid?

AA

Chronic renal failure associated with hemodialysis. What type of Amyloid?

What type of Amyloid is present in old age? (Systemic senile Amyloidosis)

ATTR (Transthyretin)

What are the types f amyloid is Ahlzeimer’s?

AB (amyloid beta protein)

What type of Amyloid is in medullary carcinoma thyroid?

Acal (calcitonin)

What type of Amyloid is in familial amyloidotic polyneuropathy?

ATTR (Transthyretin)