Cholinergic Agonists And Antagonists Flashcards

(36 cards)

1
Q

What are the categorizes cholinergic drugs?

A
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2
Q

What are the types of cholinergic agonists ?

A
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3
Q

What are the Direct-Acting cholinergic agonists?

A
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4
Q

Where are the main cholinergic receptors in the body?

A
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5
Q

What are the direct effects of acetylcholine?

A
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6
Q

What are the cardiovascular effects of ACh?

A
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7
Q

What are the effects of ACh on vasculature (endothelial)?

A

Release of NO and vasodilation

Decrease in BP

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8
Q

What’s the effect of ACh on the eye iris?

A

Miosis

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9
Q

What’s the effect of ACh on ciliary muscle?

A

Accommodation of lens to near vision

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10
Q

What’s the effect of ACh of Bronchi?

A

Constriction; increased secretions

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11
Q

What is the effect of ACh on the heart?

A

Decreased heart rate,b decreased conduction velocity

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12
Q

What is the effect of ACh on the GI tract?

A

Increased tone, peristaltic activity & secretions; relaxation of sphincters

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13
Q

What is the effect of ACh on urinary bladder?

A

Contraction of detrusor muscle, relaxation of sphincter

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14
Q

What are the nicotinic receptors of ACh?

A
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15
Q

What are the main nicotinic receptors in the body?

A
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16
Q

What’s the impact of Dale’s experiment?

17
Q

What are the types of direct-acting cholinergic agonists?

18
Q

What are the choline esters?

19
Q

What are choline esters?

20
Q

What is acetylcholine and it’s uses?

21
Q

What is benthanechol? What are its uses?

22
Q

What is carbachol and it’s uses?

23
Q

What is methacholine and it’s uses?

24
Q

What are the natural alkaloids?

A

Pilocarpine & nicotine

25
Describe pilocarpine
26
What are the uses of pilocarpine?
27
What are the adverse effects of muscuranic agonists?
28
Describe nicotine
29
What are the actions of nicotine in low doses?
30
What are the actions of nicotine?
31
Describe the acute poisoning of nicotine
32
What are the clinical nicotine uses?
33
What are the indirect-acting cholinergic agents (anticholinesterase)?
34
What are the mechanism of action indirect-acting cholinergic agents(anticholinesterases)?
35
What are the anticholinesterases?
36
What are orangophosphates?