NSAIDs Flashcards

(56 cards)

1
Q

What are NSAIDs?

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2
Q

What are the mechanisms of action of NSAIDs?

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3
Q

What is arachidonate?

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4
Q

What is arachidonic acid?

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5
Q

What synthesizes eicosanoids?

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6
Q

What are the mechanism if action of NSAIDs and the difference between the two enzymes affected?

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7
Q

What is the use of COX 2?

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8
Q

Where is COX-2 constitutive?

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9
Q

Why do some NSAIDs cause gastric damage?

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10
Q

What are the NSAIDs?

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11
Q

What are the actions of NSAIDs?

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12
Q

What are the main uses of NSAIDs?

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13
Q

How do NSAIDs help with colon cancer?

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14
Q

How do NSAIDs help with niacin tolerability?

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15
Q

How can NSAIDs be used to treat ductus arteriosus?

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16
Q

What are the adverse effects of NSAIDs?

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17
Q

What are the GI adverse effects of NSAIDs?

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18
Q

What are the relative risks of GI adverse effects of NSAIDs?

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19
Q

What are cardiovascular adverse effects of NSAIDs?

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20
Q

Describe COX-2 selective inhibition & CV risk

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21
Q

Contrast CO-1 & COX-2 CV and GI risk

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22
Q

What is celecoxib?

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23
Q

What are Rofecoxib and Valdecoxib?

24
Q

What is Meloxicam?

25
What are the renal adverse effects of NSAIDs?
26
How NSAIDs decrease blood flow?
27
Illustrate the decrease in blood flow by NSAIDs
28
What is Analgesic Neuropathy?
29
What are the renal effects of COX-2 inhibitors?
30
What is NERD? What are its symptoms ?
31
What are the causes of NERD?
32
What is an adverse effect of celecoxib?
33
What is the FDA warning of black box warning for non-aspirin NSAIDs?
34
What are the drug interactions of NSAIDs?
35
How do ACE-inhibitors interact with NSAIDs?
36
What are the drug interactions of diuretics and NSAIDs?
37
Describe the triple whammy of NSAIDs drug interactions
38
How do corticosteroids interact with NSADs?
39
How does warfarin interact with NSAIDs?
40
What is Reye’s syndrome ?
41
Is pregnancy a contraindication?
42
What are Salicylates?
43
Why is Aspirin unique among the NSAIDs?
44
What are the respiratory actions of aspirin & other salicylates?
45
Whaat are the effects of aspirin & other salicylates on platelets?
46
What are the main uses of aspirin?
47
What are the cardiovascular uses of aspirin?
48
What is Kawasaki disease?
49
How is dosage of aspirin administered?
50
How does aspirin dosage administered?
51
Describe aspirin metabolism
52
Describe aspirin adverse effects
53
Describe salicylate intoxication
54
What is Acetaminophen?
55
Describe the main uses of Acetaminophen
56
What are the adverse effects acetaminophen?