Anatomic Syndromes Flashcards

(49 cards)

1
Q

Function of orbitofrontal area:

A

Voluntary action
Decision making
Socially appropriate behavior

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2
Q

Symptoms of orbitofrontal syndrome:

A

Socially inappropriate behavior:
- Witzelsucht (joking addiction)
- Disinhibition
- Echopraxia
- Utilization behavior

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3
Q

What is utilization behavior?

A

Reaching out and using objects in the environment in an automatic manner
Reflexive picking up a cup and drinking out of it

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4
Q

Function of the dorsolateral frontal area:

A

Executive functions, working memory, and selective attention

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5
Q

Symptoms of convexity syndrome:

A

Poor attention, motor programming, and immediate recall

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6
Q

What test is good for evaluation of dorsolateral abnormalities?

A

Wisconsin Card Sorting Test

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7
Q

Mesial frontal cortex function:

A

Mediates motivated behavior, such as initiation of movement or speech

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8
Q

Symptoms of mesial frontal cortex syndrome (also known as anterior cingulate circuit syndrome)

A

Amotivation, apathy, and akinesis
B/l lesions - akinetic mutism
Patients can be incontinent and may only eat or drink when fed

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9
Q

What is the treatment for mesial frontal cortex syndrome?

A

Methylphenidate

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10
Q

Where is the lesion in a Broca’s aphasia?

A

Posterior inferior frontal gyrus

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11
Q

Where is the lesion in kluver-bucy syndrome?

A

Bilateral temporal lesions involving the amygdala

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12
Q

What the symptoms of kluver-bucy syndrome?

A

Hypermetamorphosis (urge to touch everything), compulsive eating, and hypersexuality

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13
Q

What is prosopagnosia/visual agnosia?

A

Failure to identify objects and faces by visual identification

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14
Q

What is the capgras delusion?

A

Variant of prosopagnosia in which the patient believes that a friend, spouse, or a close family member has been replaced by an impostor

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15
Q

Lesion in capgras delusion:

A

Fusiform gyrus; occipito-temporal cortex

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16
Q

Apperceptive prosopagnosia:

A

Impaired object recognition. They are unable to recognize faces. However, they may be able to recognize people based on non-face clues

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17
Q

Lesion in apperceptive prosopagnosia:

A

Right occipital-temporal area

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18
Q

Associative prosopagnosia:

A

Impaired object identification. Can copy images but can not identify an image.

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19
Q

Symptoms of associative prosopagnosia:

A

Right anterior temporal area, more often bilateral.

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20
Q

Lesion in Wernicke’s Aphasia:

A

Superior temporal gyrus

21
Q

Agraphesthesia

A

Inability to recognize letters or numbers drawn by fingertip on the patient’s skin

22
Q

Astereognosis

A

Inability to recognize an object by touch

23
Q

Ideomotorapraxia

A

Impaired understanding of tool functions
Can name a hammer but not what it does

24
Q

What is Gerstmann syndrome?

A

Agraphia, acalculia, finger agnosia, and left/right confusion

25
Lesion in Gerstmann syndrome?
Dominant inferior parietal lobe Dominant angular and supramarginal gyrus of the parietal lobe
26
What is the triad of balint syndrome?
Optic ataxia: the inability to move the hand properly to perform voluntary tasks. Visually-guided hand movements are impaired. Oculomotor apraxia: the inability to voluntarily fixate eyes to specific locations. Simultagnosia: the inability to focus on multiple objects.
27
Lesion location in balint syndrome:
Bilateral parietal-occipital lobes
28
What could cause balint syndrome?
Watershed infarcts, multiple embolic strokes, or PRES
29
Anton syndrome:
Cortical blindness The patient has true blindness, but they deny the presence of this blindness
30
Lesion in anton syndrome:
Bilateral posterior cerebral artery territory infarction
31
Achromatopsia
Colorblindness
32
Lesion in achromatopsia:
Inferior lip of the occipital lobe, often bilateral Lesion to the thalamus
33
What is limbic lobe syndrome?
Bilateral lesions in the anterior cingulate can cause akinesis and mutism
34
Alexia without Agraphia
Inability to read, but with retained ability to write
35
Lesion in what location can cause alexia w/o agraphia:
Splenium of the corpus callosum and unilateral occipital lobe
36
What can cause alexia w/o agraphia?
Unilateral posterior cerebral artery stroke
37
Limb Kinetic Apraxia lesion location:
Anterior corpus callosum
38
What is limb kinetic apraxia?
Inability to perform tasks when asked
39
Benedikt syndrome
Tegmentum midbrain CN III palsy (ipsi) Ataxia, tremor, weakness (contra)
40
Claude syndrome
Tegmentum midbrain CN III palsy (ipsi) Ataxia, tremor, vertical gaze palsy (contra)
41
Dejerine syndrome
Medial medulla CN XIII palsy (ipsi) Hemiplegia, +/- position/vibration loss (contra)
42
Locked in syndrome
Central pons B/l paralysis below neck
43
Marie-Foix syndrome
Rostral pons, AICA and basilar perforators Contralateral hypoesthesia to pain and temp (spinothalamic) Ipsi ataxia (MCP) Contra hemiparesis (corticospinal)
44
Mollaret's syndrome
Dentate nucleus, inferior olive, red nucleus Palatal myoclonus
45
Millard-Gubler syndrome
Caudal medial pons CN VI and VII palsy (ipsi) Weakness (contra)
46
Nothnagle syndrome
Tectum midbrain CN III palsy (ipsi) Ataxia and vertical gaze palsy (contra)
47
Parinaud syndrome
Dorsal midbrain Paralysis of upward gaze and accommodation
48
Wallenberg syndrome
Lateral Medulla Ataxia, loss of pain and temp for face, weakness of soft pallet, larynx/pharynx, Horner's (ipsi) Loss of pain and temp for body (contra)
49
Weber syndrome
Medial midbrain CN III palsy (ipsi) Weakness Vertical gaze palsy (contra)