Anesthetic Flashcards

(44 cards)

1
Q

Inhalation anesthetic

A

Volatile liquid,sevoflurane, and gaseous nitrous oxide

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2
Q

Non inhalation anesthetic

A

Propofol,ketamine,etomidate, midazolam

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3
Q

Premedication agents are

A

Atropine, diazepam and midazolam

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4
Q

Sedative agents

A

Dexmedetomidine

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5
Q

Myorelaxaxants

A

Rocuronium,suxamethonium

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6
Q

Local anesthetic

A

Lidocaine,bupivacaine, benzocaine

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7
Q

Anesthesia causes

A

Amnesia,loss of consciousness,immobility

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8
Q

The stronger the drug

A

The lower MAC

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9
Q

Depth of anesthetic is controlled by

A

EEG and hemodynamic function control

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10
Q

4 stages of general anesthesia

A

Analgesia, excitement, surgical anesthesia, respiratory paralysis

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11
Q

Propofol is

A

Allosteric modulator of GABAA receptor and has hypnotic and sedative effect

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12
Q

Use of propofol

A

Maintenance of generalized anesthesia,induction anesthesia and sedation

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13
Q

Etomidate

A

GABA a allosteric modulator, sedative and hypnotic effect

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14
Q

Etomidate use

A

Induction anesthesia

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15
Q

Ketamine

A

NMDA receptor channel blocker analgesic,dissociative anesthesia

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16
Q

Ketamine use

A

Maintenance of general anesthesia, induction anesthesia and postoperative sedation

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17
Q

Dissociative anaesthesia means

A

A cataleptic condition in which the patients eyes are open,but he is not communcative

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18
Q

Sevoflurane

A

GABA receptor modulator, anesthetic effect

19
Q

Sevoflurane use

A

Maintenance anesthesia,but has arrythmogenic effect

20
Q

Malignant hyperthermia

A

Increased temp, tachycardia, respiratory failure,acidosis, rigidity and rhabdomyolysis

21
Q

Nitrous oxide

A

NMDA receptor antagonist, sedative and analgesic effect,no muscle relaxation effect

22
Q

N2O use

A

Maintenance anesthesia

23
Q

N2O causes release of

A

Endogenous opioid peptides(endorphins)

24
Q

Dexmedetomidine

A

Central alpha 2 receptor agonist

25
Dexmedetomidine effects
Sedative, anxiolytic, analgesic and sympatholytic activity
26
Dexmedetomidine use
Sedation , for short term diagnostic or surgical procedures
27
Central action myorelaxaxants
BZD
28
Local anesthetic reversibly inhibits
Sensory and or motor nerves
29
Type of local anesthesia
1.Surface or terminal,2.Infiltration anesthesia 3 Regional anesthesia
30
Regional anesthesia 3types
Spinal,epidural and wire
31
Wire anesthesia
Drug administration perineural or endoneurial,blocks trunk and plexus
32
Epidural anesthesia
Drug injected in spinal canal,nerve roots are blocked
33
Spinal anesthesia
Drug injected into subarachnoid space,nerve roots are blocked
34
Heterotrimeric sodium channels have
Alpha,beta 1 and beta 2 subunits
35
Non ionised form of local anesthetic
Penetrate through cell membrane where as ionised form binds to ion channel
36
Degrees of ionisation of local anesthetic dependent on
Pka of drug and pH of tissue
37
Most local anesthetic have
Vasodilatory effect,so often combined with vasoconstrictor
38
Systemic side effects of local anesthetic include
Cardiotoxicity and CNS toxicity
39
Amides are metabolised by
Hepatic microsomal enzyme p450
40
Lidocaine has
Anesthetic effect and class 1b antiarrhythmic effect
41
Lidocaine and bupivacaine are
Sodium channel blocker and amides
42
Benzocaine is
Amino ester and has short term action duration compared to amides,allergic reactions are common
43
Lidocaine and bupivacaine are used in
All type of anesthesia
44
Benzocaine is used only in
Surface anesthesia