Annoying last things Flashcards

(52 cards)

1
Q

The combined pill prevents pregnancy by not only providing negative feedback for FSH and LH and producing cervical mucous but also…?

A

Prevents implantation due to poor proliferation of the endometrium

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2
Q

What is thought to promote ovulation with regard to LH surge?

A

Expansion of antrum and release of prostagladins E2 and F2 increasing breakdown of graafian follicle

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3
Q

What is Tunica albuginea?

A

Serous membrane surrounding the testes

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4
Q

What is considered oligospermia?

A

<10million

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5
Q

Where does the hyposgastric plexus nerve to the bladder originate?

A

T10 - L2

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6
Q

What is the various lengths of the male urethra?

A

prostatic - 4cm

Membranous - 2 cm

Spongy - 15 cm

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7
Q

What muscle aids in the last drop of urine?

A

Bulbospongious muscle

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8
Q

What are the eosiniphilic hyaline proteins found in the prostate?

A

Corpora amyleaca

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9
Q

What is the histology of the prostate?

A

Glandular columnar epithelium surrounded by muscular stroma tissue

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10
Q

What does the prostate secrete?

A

Citrate

Acid phsophatases

digestive clots and clotting proteins

Calcium

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11
Q

Which male reproductive gland secretes prostagladins?

A

semenviscles

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12
Q

What virus causes shingles?

A

Herpes Zoster

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13
Q

In the Rough Endoplasmic reticulum newly formed proteins have glucose on them which is removed by an enzyme - what is the enzyme name? and how many glucose molecules does it remove at first and why is this?

A

Glucosidase

Removes all but one - which allows chaperons (calnexin) to bind.

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14
Q

Which sub unit of the prosteosomes secretes proteolytic enzymes?

A

Beta sub-unit

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15
Q

Outline the sorbitol pathway

A

glucose > Sorbitol via Aldose reductase

Sorbitol > fructose via Sorbitol dehydrogenase

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16
Q

MMSE - components:

A
  1. Orientation to time:
    * testing hippocampus and medial temporal
  2. Orientation to place:
    * Usually testing Retrograde. also temporal frontal
  3. Registration: (apple, penny, table)
    * testing working memory (PFC) and Wernickes and Brocas
  4. Attention and calculation (-7)
    * testing PFC, parietal on dominant and cingulate gyrus
  5. Recall: (apple penny table)
    * testing ability to learn. Hippocampus
  6. Naming (pencil, watch)
    * testing wernickes and brocas
  7. Repetition: (no ifs ands or buts)
    * testing brocas and weirnkes
  8. Comprehension: (folding paper and place on floor)
    * testing left parietal and temporal for memory
  9. Reading (close eyes and do it)
    * testing left parietal
  10. Writing
    * left parietal and temporal
  11. Drawing: (pentagons)
    * Right parietal (non dominant) and basal ganglia
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17
Q

What tests proprioception?

A

Romberg’s test

  • standing still for 30 seconds followed by them closing their eyes to stop the vestibular system as their eyes have nothing to fix upon.
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18
Q

In the stages of the model of change, name them along with clinical advice in each part;

A

Pre-contemplation:

  • Motivational without pressure. pressure = resistance
  • Maintain patients independence

Contemplation:
Same as before but more motivation

Preparation:

  • Give advice
  • suggest ideas
  • support the ready patients that are ready
  • set goals with them

Action:
same as above and
- build confidence

Maintenance:

  • coping strategies
  • build confidence

Relapse:

  • help to figure what happened
  • learning
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19
Q

Gene associated with Parkinson’s disease and what kind?

A

PARK 1-11

Early onset

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20
Q

What is the precusor protein to lewy bodies?

A

Alpha synuclein

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21
Q

What is prevalence?

A

Total number of cases of a disease in a population at a given time.

Calculation: total number of cases of disease / population

22
Q

What is sensitivity?

A

Ability to detect the disease if present. Percentage of correct positive results. i.e. those identified as having a disease that actually did.

23
Q

What is specificity?

A

Ability to detect disease is not present. that is the number of people that were correctly identified as not having the disease within a negative result.

24
Q

What is PPV?

A

Probability that if a person has the disease if the result is positive

25
What is NPV?
Probability someone does not have the disease if the result is negative.
26
Outline some changes that occur in the adolescent brain:
Synaptic pruning Myelination Pre-frontal development Increased activity of mesolimbic system - seeking new rewards Amygadala development - emotional responses Increased neural plasticity
27
List some associated pathologies with alcoholism:
G.I: - Oesphageal tears - vomiting - GORD - Nutrient deficiency Pancreas: - acinar atrophy - pancreatitis - fibrotic changes to ducts Liver Blood pressure increase CVA increase Nervous system: - Neuropathy - cerebellar atrophy - hydrocephalus - ventricles enlarge - drunk punch syndrome Bones - osteoporosis
28
What are the steps of bilirubim production from the reticular endothelial system?
Pyphorin ring > Biliverdin via Haem Oxygenase enzyme Biliverdin > unconjugated bilirubin via Biliverdin Reductase
29
What is agnosia?
Inability to interrupt sensory input - resulting in non recognition of objects
30
What is apraxia?
Difficulty carrying out motor tasks due to parietal damage. The patient understands the request but is unable to programme to carry it out
31
Enzyme that is up-regulated in metbaolic acidosis?
glutaminase
32
Lack of proteases leads to increased proteins within the G.I. what is the biggest risk with this?
Entero infections
33
What caueses relaxation of the gallbladder and closure of the sphincter of oddi?
VIP
34
What level does SMA come off at?
L1
35
What level does the coaliac artery come off at?
T12
36
What type of dementia can't receive anti-psychotics?
Lewy Body dementia
37
Where is AST found?
In the mitochondria of many cells, including lungs, skeletal muscle and liver. therefore it is non specific to liver
38
Where is ALT found?
IN the cytosol of liver. Although found in other cells it is not very active and is therefore relatively specific to liver.
39
Where is GGT found? and why does it rise in alcoholics?
Smooth endoplasmic reticulum. Due to it being forced out the S.E.R for alcohol metabolism by the M.E.O.S
40
Where is ALP founx in relation to the liver?
Bile Canniculi membrane. - therefore back pressure causes pressure on it to be released as seen in blockage
41
Tests to demonstrate kidney disease outside of blood results?
Urine analyse Ultrasound Blood pressure
42
Where do B cells mature?
Spleen
43
Where in the prostate are cancers most likely to develop?
Peripheral zone
44
What are the internal skeletons of the lymph nodes made out of?
Epithelial Reticular cells - type IV collagen
45
How does mumps affect sperm production?
Disrupts the blood testi barrier?
46
What does the limbic system consist of?
Cingulate gyrus Hipocampus Fornix Amygdala Mamallary bodies Prefrontal and orbital cortex
47
Prior to sending someone to the sexual health clinic for infertility, what can be done in the GP?
Progesterone levels at day 21 to show there was ovulation STI test
48
What type of protein is Ras?
G - protein intra-cellulary
49
Beck triad?
Associated with depression: Negative view on life Negative future about the future Negative about themselves
50
What is the hereditary rate in ADHD?
75%
51
How many people develop depression in their life?
20%
52
Where does depression rate in the cause for disability?
4th biggest cause