Anti Infectives Flashcards
(27 cards)
Penicillin treats what kind of bacteria
`Only gram positive
How do penicillin and Cefazolin work to kill bacteria
Beta lactam ring binding to G-Positive cell wall
Who is Cefazolin for?
Pts with active infections (respiratory, UTI, genital, and endocarditis) as well as prophylactic use
What is worst case scenario when giving Cefazolin? (2)
Allergic reaction or C. diff/other superinfections
How is cefazolin given and why
IV, food delays absorption
Who should not take Cefazolin?
Pts with renal or GI diseases or patients taking nephrotoxic drugs
What is Tetracycline used to treat?
H. Pylori (which causes stomach ulcers and turns your teeth yellow)
What are the special aspects of tetracycline administration?
On empty stomach, without milk or iron supplements
What are the major side effects of tetracycline?
GI issues, teeth yellowing, and photosensitivity
Who should not take Tetracycline?
Pregnant, oral contraceptives, children, pt with renal/hepatic impairment, anti-lipids or penicillin’s
What should you monitor for with penicillin
Electrolyte imbalance (especially in pts with diuretics) and allergic reaction
Is penicillin pregnancy safe? but…
Pregnancy safe but decrease birth control effectiveness
What is CiprofloxaciN used to treat?
gram Negative UTI, respiratory infection, and infectious diarrhea
What is Ciprofloxacin BBW?
SIT BRO GET YO ASS IN A SEAT (tendonitis/tendon rupture)
Which anti-infectives drugs do you have to schedule around antacids?
Tetracycline and ciprofloxacin
When is Vancomycin used?
Against extreme infections like MRSA and as a last resort for staph/step
What needs to be monitored with vancomycin and why?
Peak and trough because you risk red man’s syndrome
What is red man syndrome and with what drug is it associated with?
Hypotension, flushing, and a rash on upper body/face (vancomycin)
What does Candida albicans cause
Yeast infection, diaper rash, and thrush
Used prophylactically in patients with aids and bone marrow transplants
Fluconazole
What does fluconazole treat and where?
Fungal infections of CNS, bone, eye, or urinary tract
Which anti infectives are not pregnancy safe?
ciprofloxacin, Tetracycline, vancomycin, and fluconazole, nystatin (oral)
What is nystatin used for?
Oral (thrush) and topical fungal infection (stop! smelly! get away)
What is the contraindication for flucanizole?
Chronic kidney disease (think mustache man –> dad disease)
