Drugs for GI Dysfunction and Endocrine Flashcards
(22 cards)
What is Omeprazole for and how does it work?
Patients with GERD and erosive esophagitis. It’s a proton pump inhibitor.
What is there to know about omeprazole administration?
Given once, 30 minutes before the first meal of the day
Therapy is limited to 2 months due to b12 deficiency and osteoperosis
What is the antacid/heartburn drug we learned about?
Aluminum Hydroxide
What are the 2 things to know about aluminum hydroxide administration?
Must be administered 2 hours before or 1 hour after other drugs
Should not be given to those with a bowel obstruction due to it causing constipation
What is Sulfasalazine used to treat and how does it work?
Sulfasalazine is used for IBD (Crohn’s and UC) and inhibits colon inflammatory mediators
Which drug is in the same allergy class as aspirin
Sulfasalazine (treat it similarly: anticoagulants, bleeding, hepatic impairment etc)
Under which circumstances should diphenoxylate w/ atropine not be administered?
If the diarrhea is suspected to be due to an infection because you are keeping the infection in the body
What does diphenoxylate w/ atropine treat and how does it work?
It treats diarrhea by slowing peristalsis (its an opioid)
What are the 2 major D/D interaction for diphenoxylate w/ atropine?
Do not give with MAOI’s due to risk for HTN crisis
interactions with other CNS depressants
What is the bulk type laxative we learned about?
Psyllium
Who should not receive psyllium?
Undiagnosed abdominal pain or intestine/fecal impaction
What drug treatment might a patient with diabetes insipidus get?
Desmopressin
What does desmopressin achieve in a patient and how? What secondary effects does it have?
Causes body to lose less water by kidney reabsorption
Also causes widespread smooth muscle contraction and an increase in clotting factors for bleeding disorders
Who should not use desmopressin? 4
Patients with a high risk for thrombi, chronic KIDNEY disease, heart failure, and HTN
What is levothyroxine used to treat?
Low thyroid hormone
How will TSH change if patient is not receiveing enough levothyroxine
TSH will be high until therapeutic levels are reached
What are the symptoms of hyperthyroidism
Palpations, anxiety, insomnia, weight loss, and heat intolerance
Who should not reveive levothyroxine?
Severe heart issues or adrenal insufficiency
With which drug do you take as soon as you remember and not double dose?
Levothyroxine
What are the main symptoms of Addison’s Disease?
Lethargy, weight loss, dehydration, skin color changes, low bp and blood glucose
What is hydrocortisone used to treat? (2)
Steroid replacement and inflammation
What are the 7 S’s of cushing’s
Swollen (weight gain), Skinny (arms and legs), Sepsis, Sugar (high), Sight (changes), Slow taper, Stress (increase dose during times of stress)
