Anti-Thrombotic Drugs Flashcards

1
Q

Common ADP receptor (P2Y12) antagonist

A

Clopidogrel

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2
Q

G-IIb-IIIa Inhibitors

A

Abciximab

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3
Q

Fondaparinux targets what portion of the coagulation cascade? Why?

A

Xa; shortest heparin, so can only bind Xa

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4
Q

LMWH and Heparin targets what portion of the coagulation cascade

A

Xa and Thrombin

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5
Q

Warfarin targets what portion of the coagulation cascade

A

II (thrombin), VII, IX, X

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6
Q

Examples of Direct Thrombin Inhibitiors

A

Argatroban

Dabigatran

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7
Q

Examples of Factor Xa inhibitors

A

Rivaroxaban

Apixiban

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8
Q

Fondaparinux has (long/short) duration of action

A

Long

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9
Q

Why must Warfarin be bridged with heparin?

A

Also inhibits Protein C and S synthesis (anti-thrombics), so temporarily caused a pro-thrombic state in patients

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