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Step pharm > Antibiotic Association > Flashcards

Antibiotic Association Flashcards

1
Q

Gentamicin

A

Aminoglycoside

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2
Q

Cefuroxime

A

2nd gen ceph

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3
Q

Dapsone

A

Inhibit Dihydropteroate synthase (same MOA as sulfonamides but different structure)

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4
Q

Rifampin

A

Inhibit DNA Dependent RNA polymerase

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5
Q

Erythromycin

A

Macrolide 50S block translocation

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6
Q

Isoniazid

A

Decrease Mycolic acid synthesis

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7
Q

Nafcillin

A

Penicillinase resistant Penicillin

Bulky R group

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8
Q

Sulfisoxazole

A

Inhibit Dihydropteroate synthase

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9
Q

cefazolin

A

1st gen ceph

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10
Q

Enoxacin

A

Fluoroquinolone Inhibit topoisomerase IV and II (gyrase)

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11
Q

Gemifloxacin

A

Respiratory fluoroquinolone

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12
Q

Cefepime

A

4th gen ceph

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13
Q

Dicloxacillin

A

Penicillinase resistant Penicillin

Bulky R group

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14
Q

Colistin (polymixin E)

A

Cation binds and disrupts cell membrane gram -

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15
Q

Neomycin

A

Aminoglycoside

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16
Q

Ticaracillin

A

Antipseudomonal penicillin

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17
Q

Azithromycin

A

Macrolide 50S block translocation

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18
Q

Sulfadiazine

A

Inhibit Dihydropteroate synthase

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19
Q

cephalexin

A

1st gen ceph

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20
Q

Trimethoprim

A

Inhibit dihydrofolate reductase

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21
Q

Levofloxacin

A

Respiratory fluoroquinolone

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22
Q

cefotetan

A

2nd gen ceph

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23
Q

Sulfamethoxazole

A

Inhibit Dihydropteroate synthase

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24
Q

Imipenem

A

Carbapenem

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25
Q

Pyrazinamide

A

Unknown, TB treatment

26
Q

Doripenem

A

Carbapenem

27
Q

Ceftaroline

A

5th gen ceph

28
Q

Metronidazole

A

Forms toxic free radicals that damage DNA

29
Q

Cilndamycin

A

Blocks translocation 50S

30
Q

cefotaxime

A

3rd gen ceph

31
Q

Streptomycin

A

Aminoglycoside

32
Q

Rifabutin

A

Inhibit DNA Dependent RNA polymerase

33
Q

Linezolid

A

50S prevent initiation complex formation

34
Q

Daptomycin

A

Peptide disrupts cell membrane gram +

35
Q

Amoxicillin

A

Penicillinase sensitive penicillin

36
Q

Tobramycin

A

Aminoglycoside

37
Q

Ertapenem

A

Carbapenem

38
Q

Ofloxacin

A

Fluoroquinolone Inhibit topoisomerase IV and II (gyrase)

39
Q

Vancomycin

A

Peptidoglycan formation D-Ala-D-Ala

40
Q

Oxacillin

A

Penicillinase resistant Penicillin

Bulky R group

41
Q

Norfloxacin

A

Fluoroquinolone Inhibit topoisomerase IV and II (gyrase)

42
Q

Doxycycline

A

Tetracycline 30S prevent attachment aminoacyl tRNA

43
Q

Clarithromycin

A

Macrolide 50S block translocation

44
Q

Moxifloxacin

A

Respiratory fluoroquinolone

45
Q

Tigecycline

A

Glycylcyclines

46
Q

Pyrimethamine

A

Inhibit dihydrofolate reductase

47
Q

Ethambutol

A

Block arabinosyltransferase preventing carb polymerization

48
Q

Ciprofloxacin

A

Fluoroquinolone Inhibit topoisomerase IV and II (gyrase)

49
Q

Cefoxitin

A

2nd gen ceph

50
Q

Aztreonam

A

Monobactam

51
Q

Penicillin G

A

B lactam

IV

52
Q

Meropenem

A

Carbapenem

53
Q

Piperacillin

A

Antipseudomonal penicillin

54
Q

Minocycline

A

Tetracycline 30S prevent attachment aminoacyl tRNA

55
Q

Chloramphenicol

A

Blocks peptidyltransferase 50S

56
Q

Amikacin

A

Aminoglycoside

57
Q

ceftazidime

A

3rd gen ceph

58
Q

Ampicillin

A

Penicillinase sensitive penicillin

59
Q

Penicillin V

A

B lactam

Oral, acid stable

60
Q

Ceftriaxone

A

3rd gen ceph

61
Q

Methicillin

A

Penicillinase resistant Penicillin

Bulky R group

Step pharm (9 decks)

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