Cardio drug Associations

Question 1

Sotalol

Answer 1

Class III beta blocker Block K channels, prolonging phase 2,3 (Soda)

Question 2

Beta blockers

Answer 2

Class II, Decrease slope phase 4. Decrease SA AV nodal activity. Decrease cAMP, decrease Ca current

Question 3

Ibutilide

Answer 3

Class III Block K channels, prolonging phase 2,3 (till I die)

Question 4

Lidocaine

Answer 4

Class IB, low binding Na channel, Shorten Phase 2,3 (You LIED)

Question 5

Procainamide

Answer 5

Class IA Intermediate binding Na Channel, block K channel prolong phase 2,3 (Prom King)

Question 6

Nitroprusside

Answer 6

Direct release NO, dilate veins and arteries (nitro-pressure speed boat)

Question 7

Amiodarone

Answer 7

Class III, but actually combination of all antiarrhythmics

Question 8

Propafenone

Answer 8

Class IC, high binding Na channel, drastically prolonged phase 0, no change AP duration (purple phone)

Question 9

Quinidine

Answer 9

Class IA Intermediate binding Na Channel, block K channel prolong phase 2,3 (prom queen)

Question 10

Milrinone

Answer 10

PDE3 inhibitor, increase cardiac contractility and arteriolar vasodilation (one in a million)

Question 11

Amlodipine

Answer 11

Dihydropyridine

Question 12

diltiazem

Answer 12

non dihydropyridine (delicious dark chocolate)

Question 13

nicardipine

Answer 13

Dihydropyridine (nice card)

Question 14

Nitroglycerin

Answer 14

nitrate, dilate veins&raquo_space; arteries

Question 15

Hydralazine

Answer 15

increase cGMP, vasodilates arterioles>veins (Hydro boat)

Question 16

Alirocumab

Answer 16

PCSK9 inhibitor, prevent degradation LDL receptors (doc oc)

Question 17

isosorbide mononitrate

Answer 17

nitrate, dilate veins&raquo_space; arteries (single stick)

Question 18

Niacin

Answer 18

(loch niacin monster)

Question 19

Pravastatin

Answer 19

HMG CoA reductase inhibitor (steam punk pirate)

Question 20

Evolocumab

Answer 20

PCSK9 inhibitor, prevent degradation LDL receptors (doc oc)

Question 21

Bezafibrate

Answer 21

Fibrate, upregulate PPAR alpha, increase LPL (jelly fish)

Question 22

Flecainide

Answer 22

Class IC, high binding Na channel, drastically prolonged phase 0, no change AP duration (flakes)

Question 23

Gemfibrozil

Answer 23

Fibrate, upregulate PPAR alpha, increase LPL (jelly fish)

Question 24

Fenoldopam

Answer 24

D1 agonist –> increase cAMP. Coronary and renal dilation (old lady pam)

Question 25

Adenosine

Answer 25

Activate A1 receptors –> increase K out and decrease Ca in –> inhibits AV node (swing dancing)

Question 26

clevidipine

Answer 26

Dihydropyridine (clover card)

Question 27

verapamil

Answer 27

non dihydropyridine (very vanilla)

Question 28

nifedipine

Answer 28

Dihydropyridine (pregnant knife lady)

Question 29

Mexiletine

Answer 29

Class IB, low binding Na channel, Shorten Phase 2,3 (Mexican flag)

Question 30

Digoxin

Answer 30

Inhibits Na/K/ATPase, reverse Na/Ca exchanger (DJ foxglove)

Question 31

Phenytoin

Answer 31

Class IB, low binding Na channel, Shorten Phase 2,3 (friendly towing)

Question 32

nimodipine

Answer 32

Dihydropyridine (need mo dippin)

Question 33

Lovastatin

Answer 33

HMG CoA reductase inhibitor (steam punk pirate)

Question 34

Class IV

Answer 34

veramil, Diltiazem. Lengthen phase 4

Question 35

isosorbide dinitrate

Answer 35

nitrate, dilate veins&raquo_space; arteries (double stick)

Question 36

Fenofibrate

Answer 36

Fibrate, upregulate PPAR alpha, increase LPL (jelly fish)

Question 37

Nesertide

Answer 37

Synthetic BNP, increase cGMP, arteriolar and venous dilation (turn the tide)

Question 38

Ezetimibe

Answer 38

Block cholesterol absorption at ileum (rather then bile) (Z shaped eel)

Question 39

Colesevelam

Answer 39

Bile acid resin (Cho”lobster”)

Question 40

Colestipol

Answer 40

Bile acid resin (Cho”lobster”)

Question 41

Disopyramide

Answer 41

Class IA Intermediate binding Na Channel, block K channel prolong phase 2,3 (Prom queen DISAPPEARS)

Question 42

Cholestyramine

Answer 42

Bile acid resin (Cho”lobster”)

Question 43

Dofetilide

Answer 43

Class III Block K channels, prolonging phase 2,3 (till I die)