Antibiotics Flashcards

1
Q

What are some Aminoglycosides?

A

Amikacin, Gentamicin, Neomycin, Tobramycin

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2
Q

What are some Carbapenems?

A

Imipenem

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3
Q

What are some First Generation Cephalosporins?

A

Cephalexin, Cefadroxil, Cephapirin, Cefazolin

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4
Q

What are some Second Generation Cephalosporins?

A

Cefotetan, Cefoxitin

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5
Q

What are some Third Generation Cephalosporins?

A

Cefovecin (CONVENIA), Cefpodoxime, Ceftiofur, Ceftriaxone

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6
Q

What are some Fourth Generation Cephalosporins?

A

Cefepime

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7
Q

What are some Macrolides?

A

Azithromycin, Erythromycin, Tulathromycin, Tilmicosin, Tylosin

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8
Q

What are some forms of Penicillins?

A

Amoxicillin, Amoxicillin/Clavulanate, Ampicillin, Penicillin G

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9
Q

What are some forms of Tetracyclines?

A

Doxycycline, Minocycline

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10
Q

What are some forms of Lincosamides?

A

Clindamycin

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11
Q

What are some forms of Fluoroquinolones?

A

Ciprofloxacin, Enrofloxacin, Marbofloxacin, Orbifloxacin

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12
Q

What are some forms of Sulfonamides?

A

Sulfadiazine/Trimethoprim and Sulfamethoxazole/Trimethoprim (SMZ), Sulfadimethoxine (ALBON)

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13
Q

What are some forms of antibacterials?

A

Chloramphenicol, Florfenicol, Metronidazole, Rifampin, Vancomycin

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14
Q

What are some forms of Antifungals?

A

Amphotericin B, Fluconazole, Griseofulvin, Itraconazole, Ketoconazole

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15
Q

What are some forms of Antivirals?

A

Acyclovir, Famciclovir, Lysine, Oseltamivir (Tamiflu)

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16
Q

What are bactericidals?

A

kill the organism

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17
Q

What is bacteriostatic?

A

inhibits growth of organism

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18
Q

What kinds of toxicity are seen with aminoglycosides?

A

nephrotoxicity, ototoxicity

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19
Q

What are beta-lactams?

A

antibiotics that bind to and inactivate enzymes required for cell wall synthesis

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20
Q

What are beta-lactamases?

A

enzymes bacteria produce that break open that ring inhibiting the antibiotic

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21
Q

What is the alternate name for Convenia?

A

Cefovecin

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22
Q

What infections are Cephalosporins commonly used to treat?

A

skin infections, cystitis, respiratory disease

23
Q

What injectable Cephalosporin is used for surgical prophylaxis?

24
Q

What is Ceftiofur commonly used for in large animal?

A

used to treat respiratory infection in large animals and foot rot

25
What side effect can occur in horses given Erythromycin?
can sometimes cause fatal diarrhea in horses
26
What infections is azithromycin commonly used for?
Bordetella (Kennel Cough) in dogs, Mycoplasma infections, upper respiratory infections in cats
27
What does Tulathromycin treat?
respiratory infection in non-lactating dairy cattle , bovine foot rot, infectious bovine keratoconjunctivitis
28
Tilmicosin is potentially lethal to __________________.
humans, swine and horses
29
What are Tilmicosin and Tylosin used to treat?
bovine respiratory disease, diarrhea in pigs, and poultry diseases
30
Which drug is a potentiated penicillin containing clavulanic acid?
Amoxicillin/Clavulanate
31
What does Clavulanic acid do?
binds beta-lactamases and penicillinases produced by bacterial agents
32
What type of infections might we use the different Penicillins for?
susceptible infections
33
What can Tetracycline cause in young animals?
causes teeth/bone discoloration in young animals
34
What can Doxycycline cause in cats?
esophageal stricture in cats
35
What are Tetracyclines used to treat?
Tick borne diseases (Lyme), Mycoplasma infections and chlamydia (respiratory)
36
What are the side effects of Fluoroquinolones?
cartilage damage in young growing animals
37
Why should Fluoroquinolones be used only after culture and sensitivity?
there is concern for resistance
38
What Fluoroquinolones is commonly used to treat prostate infections?
Enrofloxacin
39
What are the side effects of Sulfonamides?
KCS in dogs, bone marrow suppression, rapid IV injection can cause weakness, blindness, ataxia, collapse, hemolytic anemia
40
What are Sulfonamides used for?
E. coli infection in calves, Colibacillosis in swine, prostate infections, susceptible infections
41
What is Sulfadiazine/Trimethoprim and Sulfamethoxazole/Trimethoprim (SMZ) used for?
prostate infections and MRSA
42
What is Sulfadimethoxine used for?
coccidia in dogs, Streptococcus equi in horses, shipping fever complex, bacterial pneumonia and foot rot in cattle
43
What effect does Chloramphenicol have on humans?
aplastic anemia
44
What animals is Chloramphenicol prohibited in?
food animals
45
What are the side effects of Metronidazole?
neurologic disorders (seizures), GI signs, hepatotoxicity there has been reported clostridial diarrhea and death after metronidazole use in horses
46
What is Rifampin used to treat in large animals?
R. equi in young horses
47
What are Lincosamides used to treat?
wounds/abscesses, Toxoplasma in cats, bone infections
48
What is Clindamycin commonly used to treat?
bone, dental infections, and toxoplasmosis
49
What is the treatment of choice for blastomycosis and is FDA approved for treatment of ringworm in cats?
Itraconazole
50
What antifungal is also used in Cushing's treatment?
Ketoconazole
51
MIC
Minimum Inhibitory Concentration
52
What is MIC?
the lowest concentration that shows inhibition of growth
53
What drugs are used to treat Giardia?
Metronidazole
54
What drugs are used to treat tick borne and rickettsial diseases?
Tetracyclines