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CPT Drugs > Antibiotics > Flashcards

Antibiotics Flashcards

1
Q

Trimethoprim - DDI / X

A

UTI

Folate antagonist

Teratogenic

Methotrexate - both folate antagonists (myelosupression)

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2
Q

Nitrofurantoin - ADRs / X

A

UTI

Affects protein synthesis - 50% excreted in urine

Discolouration of urine
Pulmonary fibrosis

Pregnancy X

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3
Q

Aminoglycosides

A

Gentamicin, Vancomycin, Streptomycin

Septicaemia
Pneumonia
Otitis externa
Meningitis

Inhibit protein synthesis (bind to 30s)

Nephrotoxicity / Ototoxicity

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4
Q

Penicillins

A

Amoxicillin, Co-amoxiclav, Penicillin v, Flucloxacillin

Acute choleocystitis
Resp tract infections
Sinusitis

Inhibit cell wall synthesis

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5
Q

What is co-amoxiclav?

A

clavulanic acid is a B lactamase inhibitor

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6
Q

Macrolides

A

Clarithromycin, Erythromycin

Inhibit protein synthesis

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7
Q

Cephalosporins

A

Ceftriaxone, Cefalexin

Mengincoccal sepsis

Inhibits cell wall synthesis

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8
Q

Anti-viral

A

Aciclovir

Varicella zoster
Herpes simple virus

Inhibits viral DNA syntheisis

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CPT Drugs (19 decks)

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