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Flashcards in Antibiotics Deck (48):
1

What are the two divisions of antibiotics that work on DNA replication?

Fluoroquinolones and Metronidazole

2

Name two broad spectrum fluoroquinolones

Levofloxacin and Ciprofloxacin

3

What is the mechanism of antibiotics that prevent RNA synthesis?

RNA polymerase inhibitor

4

Name some RNA polymerase inhibitor drugs?

Rifampicin
Fidaxomicin
Anti-TB drugs

5

What three classes of antibiotics prevent protein synthesis?

Macrolides
Aminoglycosides
Tetracyclines

6

Name a macrolide antibiotic?

Clarithromycin

7

Name an aminoglycoside antibiotic

Gentamicin

8

Name a tetracycline antibiotic

Doxycycline

9

What classes of antibiotics work against cell wall synthesis?

Vancomycin
B-Lactams

10

What are the three types of B-lactam antibiotics?

Penicillins
Cephalosporin
Carbapenem

11

What are the three classes of penicillins?

Broad
B-lactamase resistant
Extended spectrum

12

Name some broad spectrum penicillins

Amoxicillin

13

Name a B-lactamase resistant penicillin

Flucloxacillin

14

Name an extended spectrum penicillin

Piperacillin

15

Name two 3rd generation cephaloporins

Cefotaxime
Ceftazidime

16

Name two carbapenem

Meropenem
Imipenem

17

Name an antibiotic that prevents folate synthesis

Trimethoprim
Sulphonamide
(Co-trimoxazole)

18

What is the treatment for pneumococcal pneumonia?

Amoxicillin
Benzyl penicillin
Cephalosporin

19

What is the treatment for staphylococcal pneumonia?

Flucloxacillin
Rifampicin

20

What is the treatment for klebsiella pneumonia?

Cefotaxime or imipenem

21

What is the treatment for pseudomonas pneumonia

Anti-pseudomonal penicillin, ceftazidime, meropenem or ciprofloxacin and aminoglycoside

22

What is the treatment for mycoplasma pneumonia?

Clarithromycin or doxycycline or a fluoroquinolone

23

What is the treatment for legionella pneumonia?

Fluoroquinolone or clarithromycin

24

What is the treatment for chlamydophilia psittaci?

Doxycycline or clarithromycin

25

What is the treatment for pneumocystis pneumonia?

High dose co-trimoxazole or pentamidine IV

26

What is the treatment for severe proven spontaneous bacterial peritonitis?

Piperacillin/Tazobactam
Then
Co-trimoxazole

27

What is the treatment for mild proven spontaneous bacterial peritonitis?

Co-trimoxazole

28

What is the treatment for non-severe C. diff?

Metronidazole

29

What is the treatment for severe C. diff?

Vancomycin +/- Metronidazole

30

What is the treatment for recurrent C. diff?

Fidaxomicin

31

What is the treatment for Native valve indolent (subacute) endocarditis?

Amoxicilllin Gentamicin

32

What is the treatment for Native valve severe sepsis (acute) endocarditis?

Flucloxacillin

33

What is the treatment for Prosthetic valve MRSA endocarditis?

Vancomycin Rifampicin Gentamicin

34

What is the treatment for Native valve severe sepsis and risk factors of specific resistance endocarditis?

Vancomycin Meropenem

35

What is the treatment for enterococcus endocarditis?

Amoxicillin Vancomycin Gentamicin

36

What is the treatment for Viridans endocarditis?

Penicillin Gentamicin

37

What is the treatment for IV drug user endocarditis?

Flucloxacillin

38

What is the treatment for Epidermidis endocarditis?

Vancomycin Gentamicin

39

What is the treatment for peritonitis/biliary/intra-abdominal?

IV Amoxicillin Metronidazole Gentamicin
Then
PO Co-trimoxazole Metronidazole

40

What is the 1st line treatment for an acute exacerbation of COPD?

Amoxicillin 500mg tds

41

What is the 2nd line treatment for an acute exacerbation of COPD?

Doxycycline 200mg day one then 100mg (5 days)

42

What is the 1st line treatment for acute cough/bronchitis?

Amoxicillin 500mg tds

43

What is the 2nd line treatment for acute cough/bronchitis?

Doxycycline 200mg day one then 100mg after

44

What is the treatment for mild/moderate CAP?

Amoxicillin (IV/PO 5 Days)
If penicillin allergic Doxycycline

45

What is the treatment for severe CAP?

Co-amoxiclav IV + Doxycycline PO
*If penicillin allergic Levofloxacin

46

What is the treatment for ICU/HDU CAP?

Co-amoxiclav IV + Clarithromycin IV
Then
Doxycycline
*If penicillin allergic Levofloxacin

47

What is the treatment for severe HAP?

IV Amoxicillin+ Metronidazole + Gentamicin
Step down to PO Co-trimoxazole + Metronidazole

*If penicillin allergic IV Co-trimoxazole + Metronidazole +/- Gentamicin

48

What is the treatment for non-severe HAP?

PO Amoxicillin + Metronidazole
*If penicillin allergic PO Co-trimoxazole + Metronidazole