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Flashcards in Antibodies Deck (24)
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1

anti-postsynaptic ACh receptor

Myasthenia gravis

2

anti-presynaptic voltage-gated calcium channel

LEMS

3

antiphospholipid

anti-beta2 glycoprotein 1, anticardiolipin

4

SLE

ANA (nonspecific often a/w), anticardiolipin, anti-dsDNA, anti-Smith

5

antihistone

drug induced lupus

6

anti-U1 RNP

mixed CT disease

7

RA

RF (IgM antibody against IgG), anti-CCP (more specific)

8

anti-Ro/SSA, anti-La/SSB

Sjogren

9

anti-Scl70 (anti-DNA topoisomerase I)

scleroderma (diffuse)

10

anticentromere

CREST

11

anti-synthetase (anti-Jo1), anti-SRP, anti-helicase (anti-Mi-2)

polymyositis, dermatomyositis

12

antimitochondrial

primary biliary cholangitis

13

anti-smooth muscle, anti-liver/kidney microsomal-1

autoimmune hepatitis

14

MPO-ANCA/p-ANCA

microscopic polyangiitis, eosinophilic granulomatosis w/ polyangiitis, UC, primary sclerosing cholangiitis

15

PR3-ANCA/c-ANCA

granulomatosis w/ polyangiitis

16

anti-phospholipase A2 receptor

primary membranous nephropathy

17

anti-hemidesmosome

bullous pemphigoid

18

anti-desmoglein (anti-desmosome)

pemphigus vulgaris

19

antithyroglobulin, antithyroid peroxidase

Hashimoto thyroiditis

20

anti-TSH receptor

Graves

21

IgA anti-endomysial, IgA anti-tissue transglutaminase (TTG), IgA and IgG deamidated gliadin peptide

Celiac

22

anti-glutamic acid decarboxylase, islet cell cytoplasmic antibodies

T1DM

23

antiparietal cell, anti-IF

pernicious anemia

24

anti-GBM

Goodpasture