Tumor Markers Flashcards Preview

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Flashcards in Tumor Markers Deck (13)
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1

CA 19-9

liver/biliary/pancreas (pancreatic adenocarcinoma)

2

CA 15-3, CA 27-29

breast cancer

3

CA 125

ovarian cancer

4

HER2/Neu

breast and gastric

5

AFP

hepatocellular, yolk sac, mixed germ cell tumors, ataxia-telangiectasia, neural tube defects

6

hCGbeta

Hydatidiform moles and Choriocarcinomas (Gestational trophoblastic disease), testicular cancer, mixed germ cell

7

S100

melanoma

8

PSA

prostate

9

calcitonin

medullary thyroid (alone and in MEN2A, 2B) calci2nin

10

CEA

colorectal/pancreas; nonspecific

11

chromogranin

neuroendocrine tumors

12

alkaline phosphatase

mets to bone or liver, Paget disease, seminoma

13

LDH

testicular germ cell tumor, ovarian dysgerminoma, others