anticoagulant drugs and antiplatelets Flashcards Preview

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Flashcards in anticoagulant drugs and antiplatelets Deck (18):
1

indications for anticoagulant drugs

venous thrombosis
atrial fibrillation

2

what drug potentiated antithrombin

heparin

3

what are the 2 forms of heparin

unfractionated
low molecular weight

4

how do you monitor low molecular weight heparin

anti- xa assay

5

how do you monitor unfractionated heparin

APTT

6

how can heparin be give

IV or SC

7

what are the complications of heparin

bleeding
osteoporosis with long term use
heparin induced thrombocytopenia

8

how does warfarin work

vitamin K antagonist

9

where is vit K absorbed

upper intestine

10

what do you need to absorb vitamin K

bile salts

11

what are the vit K dependent factors

II
VII
IX
X

12

when should warfarin be taken

same time everyday
6pm is recommended

13

how does dabigatran work

thrombin inhibitor

14

how does rivaroxaban work?

Xa inhibitors

15

how does aspirin work?

inhibits cyclo-oxygenase

16

side effects of asprine

GI bleed
bronchospasm- dont take if asthma
GI ulceration

17

how does clopidogrel work

ADP receptor antagonist

18

how does dipyridamole work

phospodresterase inhibitor- reduces cAMP production