Anticoagulants nursing pharmacology students need to know

Question 1

What is the generic name for Coumadin?

Answer 1

Warfarin

Question 2

What class of drug is Warfarin?

Answer 2

Vitamin K antagonist

Question 3

What is the primary action of Warfarin?

Answer 3

Inhibits vitamin K-dependent clotting factors

Question 4

True or False: Warfarin is an anticoagulant.

Answer 4

True

Question 5

What is the generic name for Lovenox?

Answer 5

Enoxaparin

Question 6

What class of drug is Enoxaparin?

Answer 6

Low molecular weight heparin

Question 7

What is the primary action of Enoxaparin?

Answer 7

Inhibits factor Xa and IIa

Question 8

Fill in the blank: Enoxaparin is used for the prevention and treatment of __________.

Answer 8

Deep vein thrombosis (DVT)

Question 9

What is the generic name for Arixtra?

Answer 9

Fondaparinux

Question 10

What class of drug is Fondaparinux?

Answer 10

Factor Xa inhibitor

Question 11

What is the action of Fondaparinux?

Answer 11

Inhibits factor Xa

Question 12

True or False: Fondaparinux can be used in patients with a history of heparin-induced thrombocytopenia.

Answer 12

True

Question 13

What is the generic name for Pradaxa?

Answer 13

Dabigatran

Question 14

What class of drug is Dabigatran?

Answer 14

Direct thrombin inhibitor

Question 15

What is the primary action of Dabigatran?

Answer 15

Directly inhibits thrombin

Question 16

Fill in the blank: Dabigatran is an oral anticoagulant used to prevent __________.

Answer 16

Stroke in patients with atrial fibrillation

Question 17

What is the generic name for Xarelto?

Answer 17

Rivaroxaban

Question 18

What class of drug is Rivaroxaban?

Answer 18

Factor Xa inhibitor

Question 19

What is the primary action of Rivaroxaban?

Answer 19

Inhibits factor Xa

Question 20

True or False: Rivaroxaban requires routine monitoring of INR.

Answer 20

False

Question 21

What is the generic name for Eliquis?

Answer 21

Apixaban

Question 22

What class of drug is Apixaban?

Answer 22

Factor Xa inhibitor

Question 23

What is the action of Apixaban?

Answer 23

Inhibits factor Xa

Question 24

Fill in the blank: Apixaban is used for the prevention of __________ after hip or knee replacement surgery.

Answer 24

Deep vein thrombosis (DVT)

Question 25

What is the generic name for Savaysa?

Answer 25

Edoxaban

Question 26

What class of drug is Edoxaban?

Answer 26

Factor Xa inhibitor

Question 27

What is the primary action of Edoxaban?

Answer 27

Inhibits factor Xa

Question 28

True or False: Edoxaban is indicated for the treatment of non-valvular atrial fibrillation.

Answer 28

True

Question 29

What is the generic name for Angiomax?

Answer 29

Bivalirudin

Question 30

What class of drug is Bivalirudin?

Answer 30

Direct thrombin inhibitor

Question 31

What is the action of Bivalirudin?

Answer 31

Directly inhibits thrombin

Question 32

Fill in the blank: Bivalirudin is often used in patients undergoing __________.

Answer 32

Percutaneous coronary intervention (PCI)

Question 33

What is the generic name for Refludan?

Answer 33

Lepirudin

Question 34

What class of drug is Lepirudin?

Answer 34

Direct thrombin inhibitor

Question 35

What is the primary action of Lepirudin?

Answer 35

Directly inhibits thrombin

Question 36

True or False: Lepirudin is derived from leeches.

Answer 36

True

Question 37

What is a common adverse effect of Warfarin?

Answer 37

Bleeding

Question 38

What monitoring is required for patients on Warfarin?

Answer 38

INR monitoring

Question 39

Fill in the blank: Patients taking Enoxaparin should be monitored for __________.

Answer 39

Thrombocytopenia

Question 40

What is a common adverse effect of Dabigatran?

Answer 40

Gastrointestinal bleeding

Question 41

True or False: Fondaparinux can be administered subcutaneously.

Answer 41

True

Question 42

What is the antidote for Warfarin?

Answer 42

Vitamin K

Question 43

What is the antidote for Dabigatran?

Answer 43

Idarucizumab

Question 44

What is the common route of administration for Rivaroxaban?

Answer 44

Oral

Question 45

Fill in the blank: Apixaban should be taken __________ with food.

Answer 45

Twice daily

Question 46

What is a potential adverse effect of Rivaroxaban?

Answer 46

Hematoma

Question 47

True or False: Anticoagulants are used to dissolve existing clots.

Answer 47

False

Question 48

What is the mechanism of action for vitamin K antagonists?

Answer 48

Inhibit the synthesis of vitamin K-dependent clotting factors

Question 49

What is a primary indication for using anticoagulants?

Answer 49

Prevention of thromboembolic events

Question 50

Fill in the blank: Long-term use of Warfarin requires __________.

Answer 50

Regular INR monitoring

Question 51

What is the preferred anticoagulant for patients with mechanical heart valves?

Answer 51

Warfarin

Question 52

What is a contraindication for using Dabigatran?

Answer 52

Active bleeding

Question 53

What is the half-life of Rivaroxaban?

Answer 53

5 to 9 hours

Question 54

Fill in the blank: Patients on anticoagulants should be educated about the signs of __________.

Answer 54

Bleeding

Question 55

What is the effect of food on the absorption of Rivaroxaban?

Answer 55

Increases absorption

Question 56

What is the main advantage of using low molecular weight heparins over unfractionated heparin?

Answer 56

Lower risk of heparin-induced thrombocytopenia

Question 57

Fill in the blank: The recommended starting dose of Warfarin is __________.

Answer 57

2 to 5 mg

Question 58

What should be monitored when a patient is on Enoxaparin?

Answer 58

Platelet count

Question 59

What is a unique property of Fondaparinux?

Answer 59

Does not require monitoring of anticoagulation

Question 60

What is the risk of using anticoagulants in patients with liver disease?

Answer 60

Increased bleeding risk

Question 61

Fill in the blank: Anticoagulants should be used cautiously in patients with __________.

Answer 61

Renal impairment