Antidepressants

Question 1

Mixed 5HT/NE reuptake inhibitor

Answer 1

TCA
Venlafaxine
Desvenlafaxine
Duloxetine

Question 2

Venlafaxine

Answer 2

Effexor

Question 3

Venlafaxine SE

Answer 3

Agitation, HA, insomnia, sexual dysfunction, increase diastolic BP**

Question 4

Desvenlafaxine

Answer 4

Pristiq

Question 5

Duloxetine

Answer 5

Cymbalta

Question 6

Duloxetine AE

Answer 6

CNS (sedation, dizziness, HA, insomnia)
GI (N/V/D)
Xerostomia
**changes in BP (caution with uncontrolled HTN)

Question 7

SSRIs

Answer 7

Fluoxetine
Paroxetine 
Sertraline 
Fluvoxamine
Citalopram 
Escitalopram

Question 8

Fluoxetine

Answer 8

Prozac

Question 9

Paroxetine

Answer 9

Paxil

Question 10

Sertraline

Answer 10

Zoloft

Question 11

SSRI SE

Answer 11

Nausea, insomnia, HA, weight neutral
Sedation, sexual dysfunction
Initial increase in anxiety

Question 12

Paxil SE

Answer 12

Anticholinergic

Question 13

Zoloft SE

Answer 13

GI (diarrhea and loose stools)

Question 14

Mixed serotonin effects

Answer 14

Trazodone

Nefazodone

Question 15

Trazodone

Answer 15

Desyrel

Question 16

Nefazadone

Answer 16

Serzone

Question 17

Nefazodone SE

Answer 17

Sedation, orthostasis, dry mouth, nausea

Black Box: **liver failure

Question 18

Nefazadone benefits

Answer 18

Less sexual dysfunction, agitation, and weight changes

Question 19

Mixed NE/DA reuptake inhibitor

Answer 19

Bupropion

Question 20

Bupropion SE

Answer 20

Agitation, nausea, HA, seizures, tremor, insomnia

Question 21

Bupropion benefits

Answer 21

Less sexual dysfunction

Less likely to induce mania

Question 22

Bupropion disadvantages

Answer 22

Higher seizure potential

AVOID in pets with pre-existing seizures, bulimia, anorexia, alcohol withdrawal

Question 23

Mixed 5HT/NE effects

Answer 23

Mirtazapine

Question 24

Mirtazapine

Answer 24

Remeron

Question 25

Mirtazapine SE

Answer 25

Sedation (doses <15mg) Increase appetite, weight gain Increase total cholesterol, TG, glucose dysregulation Dry mouth, constipation, orthostasis

Question 26

MAOI

Answer 26

Phenelzine Tranylcypromine Selegiline

Question 27

MAOI SE

Answer 27

DDI/DFI: hypertensive crisis—stroke | Selegiline transdermal is less

Question 28

TCA SE

Answer 28

Anticholinergic, antihistamine, hypotension, sedation, tachycardia, weight gain, sexual dysfunction, decrease seizure threshold

Question 29

TCAs

Answer 29

``` Amitriptyline Amoxapine Desipramine Doxepin Imipramine Nortriptyline Protriptyline Trimipramine ```

Question 30

Serotonin syndrome

Answer 30

GI symptoms, tremors, hyperreflexia, restlessness, tachycardia, HTN, manic-like symptoms, confusion, hyperpyrexia

Question 31

Discontinuation syndrome

Answer 31

Vivid dreams, nightmares, tremor, dizziness, crying spells, nausea, poor concentration