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OCTAVO SEMESTRE > Antidiabeticos > Flashcards

Antidiabeticos Flashcards

1
Q

heparina no fracciona con que se monitoriza

A

PTT

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2
Q

Que neutraliza la heparina

A

Protamina

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3
Q

mecanismo de inhibidores directos de la trombina

A

Se unen en el sitio activo de la trombina

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4
Q

Que es dabigatran

A

inhibores directos de la trombina

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5
Q

que revierte el efecto de dabigatran

A

Idarucizumab

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6
Q

inhibidores directos del factor 10A

A

Apixaban, rivaroxaban

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7
Q

revierte el efecto de los inhibidores directos del factor 10 A

A

andexanet alfa

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8
Q

como se monitoriza la warfarina

A

INR

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9
Q

Revierte el caso de warfarina

A

vitamina K

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10
Q

mecanismo clopidrogel

A

inhibe de forma
irreversible al receptor del
ADP plaquetario

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11
Q

Insuilinas pandriales

A

regular, lisina, glulisina, aspart

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12
Q

insulinas basales

A

NPH, detemir, glargina 100 y 300, degludec

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13
Q

secretagogos de insulina cuales son

A

sulfinilureas y megliptinidas

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14
Q

cual es el biguanida

A

metformina

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15
Q

quien modifica la microbiota intestinal

A

metformina

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16
Q

efectos adversos de mertformina

A

diarrea, deficiencia de vitamina B12 con el uso cronico.
raro: acidosis lactica

17
Q

efecto neutro sobre el peso

A

merftormina

18
Q

MEDICAMENTOS agonistas del receptor de GLP1

A

exanaltide, semaglutide, liraglutide, dulaglutide

19
Q

efectos adversos de la liraglutide

A

nauseas, anorexia, constipacion

20
Q

liraglurtide provoca perdida de peso

A

si

21
Q

dosis para bajar de peso con liraglutide

A

3 mg/ dia

22
Q

semaglutide generalidades

A

baja de peso, dm2, reduce el riesgo cardiovascular . es oral y parenteral

23
Q

inhibodores de los SGLT2

A

Empaglifozina y dapaglifozina

24
Q

mecanismos de los SGLT2

A

aumentan la excrecion de glucosa

25
Q

generalidades de los SGT2

A

REDUCEN 1.5 a 2 kilos
reducen la mortalidad en falla cardiaca con FE reducida
baja el riesgo cardivascular

26
Q

efectos adversos de los SGLT2

A

infecciones del tracto urinario
hipotension a
cetoacidosis
gangran de fourner

27
Q

ajuste renal de la empaglifozina y la dapaglifozina

A

empa: contraindica en tfg menor de 30
dapa: menor de 45 en diabeticos
menor de 25 resto de gente

28
Q

mecanismos de los inhibidores de dpp4

A

incrementan los niveles de incretinas endogenas

29
Q

efectos adversos de los DPP4

A

molestias gastrointestinales (nasuseas, dolor constipacion)
cefalea
pancreatitis
angioedema

30
Q

duración de las insulinas prandiales

A

regular 6/8 h
glulisina 4 h
lisina 4h
aspart 4h

31
Q

duración de las insulinas basales

A

NPH 12-14 H
glargina 100 24
300 37

OCTAVO SEMESTRE (28 decks)

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