intoxicación por metanol Flashcards

1
Q

donde se metaboliza

A

higado

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2
Q

por que enzima es metabolizado

A

alcohol deshidrogenasa

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3
Q

quien es responsable de la toxicidad

A

acido fórmico

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4
Q

quien se encarga de eliminar el formato

A

folato

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5
Q

en que se disocia el acido formico

A

hidrogeno
folato

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6
Q

manifestaciones clinica

A
  • Anorexia
  • Confusión
  • Cefalea
  • Malestar general
  • Debilidad
  • Nauseas
  • Hiperventilación
  • Alteraciones visuales
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7
Q

secuelas

A
  • neuropatia optica
  • infarto de ganglios basales con parkinsonismo
  • encefalopatia toxica
  • polineuropatia
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8
Q

dosis letal

A

1.2 mg/kg
30-240 ml

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9
Q

tratamiento

A
  • etanal
  • acido folico 50 mg IV c/4 horas
  • eritropoyetina 20.000 X3 dias
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10
Q
A
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