Antihistamines Flashcards Preview

Pharm Exam 6 > Antihistamines > Flashcards

Flashcards in Antihistamines Deck (18):
0

Diphenhydramine

(Benadryl) 1st gen H1 antagonist
Enters CNS- high sedation, anticholinergic-motion sickness
CI: children

1

Dimenhydrinate

(Dramamine) 1st gen H1 antagonist
Enters CNS- high sedation, anticholinergic-motion sickness
CI: children

2

Doxylamine

(Unisom)- Sleep aid
1st gen H1 antagonist
Enters CNS- high sedation, anticholinergic-motion sickness
CI: children

3

Promethazine

(Phenergan) 1st gen H1 antagonist
Anti-emetic
Enters CNS- high sedation, anticholinergic-motion sickness
CI: children

4

Hydroxyzine

(Atarax, Vistaril) 1st gen H1 antagonist
For vertigo
Enters CNS- high sedation, anticholinergic-motion sickness
CI: children

5

Brompheniramine

(Bromamine, Dimetane) 1st gen H1 antagonist
moderate sedation
CI: children

6

Chlorpheniramine (Chlor- Trimeton)

1st gen H1 antagonist
moderate sedation
CI: children

7

Cyclizine (merezine)

1st gen H1 antagonist
moderate sedation, motion sickness-anticholinergic
CI: children

8

Clemastine (Tavist)

1st gen H1 antagonist
moderate sedation
CI: children

9

Meclizine (Bonine)

1st gen H1 antagonist
moderate sedation
CI: children

10

Loratidine

(Claritin)
2nd gen H1 antagonist -Non sedating, not anticholinergic
OD: arrhythmias

11

Desloratadine

(Clarinex) - active metabolite
2nd gen H1 antagonist -Non sedating, not anticholinergic
OD: arrhythmias

12

Certirizine

(Zyrtec)
2nd gen H1 antagonist -Non sedating, not anticholinergic
Mild sedation, may also inhibit histamine release from mast cells
Ok in liver disease
OD: arrhythmias

13

Levocetirizine

(Zyxal) - R enantiomer
2nd gen H1 antagonist -Non sedating, not anticholinergic
Ok in liver disease
OD: arrhythmias

14

Acrivistine
Pseudoephedrine

(Semprex)
2nd gen H1 antagonist -Non sedating, not anticholinergic
Ok in liver disease
OD: arrhythmias

15

Fexofenadine

(Allegra)
2nd gen H1 antagonist -Non sedating, not anticholinergic
OD: arrhythmias

16

Cromolyn Sodium (Intal, Aarane)
Nedcromil (Tilade)

Inhibits release of histamine from mast cells
Inhaled
For astma (esp children)

17

Azelastine (Astelin NS, Astepro)

Intranasal - Noncompetitive H1 blocker and dec release of histamine
tx: allergic rhinitis