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Flashcards in Antihistamines Deck (2)
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What aspect of first-generation antihistamines makes them sedating?

They have anti-cholinergic effects and can cross the BBB.


A parent of a 13 year old with bad allergic rhinitis has been giving her child diphenhydramine at bedtime due to symptoms but he has started acting bizarrely at night. What should you advise she do?

Stop diphenhydramine. He is having a paradoxical reaction.