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Flashcards in Mastocytosis Deck (8)
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1

What is urticaria pigmentosa?

Darker urticaria associated with mastocytosis.

2

What is mastocytosis?

A rare disorder characterized by abnormal mast cell proliferation.

3

What are the three broad categories of mastocytosis?

Cutaneous (urticaria pigmentosa)
Systemic
Malignant

4

What lab test can be used to screen for cutaneous mastocytosis?

Tryptase

5

What is Darier's sign?

Wheal developed after gently stroking urticaria pigmentosa (cutaneous mastocytosis).

6

Patients with mastocytosis should avoid triggers that cause mast cell degranulation. What are these typical triggers?

Cold
Heat
Alcohol
Aspirin
Opiates

7

What medication can be given for mastocytosis?

Cromolyn which can help stabilize mast cells.

8

A 7 year old is seen for large, hyperpigmented raised areas all over his back. Gently stroking an area causes a wheal. What serum test could help confirm the diagnosis?

Tryptase level > 20. This could be cutaneous mastocytosis (urticaria pigmentosa)