Immune System Structure Flashcards Preview

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Flashcards in Immune System Structure Deck (12):
1

How many classes of HLA exist?

There are three classes:HLA I is found on all nucleated cells.HLA II is found on antigen presenting cells.

2

What is the difference in function between HLA class I and HLA class II?

HLA class one is the "self "molecule found on all nucleated cells. HLA class two is found on antigen presenting cells.HLA I presents to CD8HLA II presents to CD4

3

What is the difference in function between Th1 and Th2 cells?

Th1 induces CD8 cells. Th2 induces B cells

4

How are NK T cells and NK cells different?

NK T cells recognize lipid and glycolipds presented by CD1. NK cells are always in KILL mode unless they are turned off by HLA-E on self cells.

5

You are studying a cell that requires CD1 to function properly. What type of cell are you studying?

NK T cells

6

True or false: B cells can act as antigen presenting cells.

True

7

Regulatory T cells express FoxP3 controlling the immune system. What modulators are involved in this regulation?

IL – 10TGF – b

8

Which antibody types can activate complement?

IgG and IgM

9

What are the three different complement binding pathways? On which complement step do they all converge?

ClassicalMannose bindingAlternativeC3a

10

Which complement step triggers opsonization?

C3b

11

Which complement step promotes inflammation, triggering chemotaxis, leukocyte activation, and mast cell degranulation?

C5a

12

Which chromosome carries genes for human leukocyte antigens? (HLA)

Chromosome 6