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1

What substances are most commonly associated with anaphylactoid reactions? Are these mediated by IgE?

NSAIDs
Aspirin
Radiographic contrast

2

Previously sensitized T cells interact with an antigen causing an inflammatory reaction that peaks in 24-72 hours. What type of hypersensitivity is this?

Type IV cell mediated.

3

What type of hypersensitive is seen in antibody-antigen mediated reactions?

Type III as in RA, some drug reactions.

4

What is the most likely diagnosis in a child with the following scenario: he was just started on PCN, has never had it before, he develops the following after 8 days:

Fever
Nausea/vomiting
Skin rash with redness, itching, urticaria, angioedema
Joint pain of the knees and ankles
Lymph node swelling
Muscle aches
Proteinuria

Serum sickness which is a type III hypersensitivity reaction.

5

In infants with atopic dermatitis, what is the typical skin distribution of lesions?

Extensor

6

Anaphylaxis to an allergen is mediated by what immunoglobulin?

IgE