Antiviral #1 Flashcards Preview

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Flashcards in Antiviral #1 Deck (14):
1

Immune Globulin

Use: Hepatitis, measles, Rabies, Polio

Mechanism: Increase passive immunity, prevention of infectious disease

2

Palivizumab

Use: RSV

Mechanism: Antibody neutralizes RSV

3

Amantadine

Use: Influenza A

Mechanism: Block viral penetration and uncoating

4

Zanamivir

Use: All flu viruses

Mechanism: inhibition of neuroaminidase (decrease release of new virus)

5

Oseltamivir

Use: influenza A and B

Mechanism: neuroaminidase inhibitor

6

Ribavirin

Use: Hep C (hemolytic anemia), RSV

Mechanism: DNA and RNA synthesis inhibition (purine nucleoside analog)

7

Trifluridine

Use: Topical treatment keratoconjunctivitis (HSV)

Mechanism: inhibits viral and cellular DNA polymerase

8

Acyclovir

Use: Mucosal, cutaneous, systemic HSV. Genital Herpes, VZV

Mechanism: inhibits viral DNA polymerase (antimetabolite with selectivity vs virus)

9

Gancyclovir

Use: CMV retinitis

Mechanism: DNA synthesis inhibition

10

Foscarnet

Use: CMV pts w/ AIDS

Mechanism: inhibits viral pol but not cellular

11

Tenofovir

Use: Hep B

Mechanism:

12

Lamivudine

Use: Hep B

Mechanism:

13

Emtrictabine

Use: Hep B

Mechanism:

14

Interferon alpha-2b

Use: Genital and anal warts, Hep B, Hep C +ribavirin

Mechanism: