Antiviral And Antiretroviral Drugs Flashcards
(21 cards)
Name NRTIs
Zidovudine
Lamivudine
Stavudine
Emtricitabine
Tenofovir
Abacavir
Didanosine
Name NNRTIs
Nevirapine
Efavirenz
Etravirine
Delavirdine
Doravirine
Rilpivirine
(NEED Rti)
DOC in prevention of perinatal transmission of HIV
Nevirapine
NNRTI that can be used w Rifampicin
Efavirenz
Regimen for HIV treatment and Post exposure prophylaxis
Tenofovir + Lamivudine + Dolutegravir / 2 Lopinavir/Ritonavir / 3 Efavirenz
Side effects of NRTI
Lactic acidosis, peripheral neuropathy, myopathy and pancreatitis
(Due to mitochondrial toxicity)
SJS is a side effect of which antiretroviral
Nevirapine
Only NRTI ineffective in HIV2 is
Abacavir
Which Protease inhibitor is used as a boost and why?
Ritonavir - strong microsomal inhibitory action , can competitively inhibit metabolism of other PIs
Cobicistat is used w which drugs?
Atazanavir, Darunavir, Elvitegravir
Protease inhibitors
Ritonavir
Atazanavir
Indinavir
Nelfinavir
Saquinavir
Fosamprenavir
Lopinavir
Darunavir
Classes under antiretrovirals
NRTIS
NNRTIS
Integrase inhibitor
Protease inhibitors
CCR5 receptor inhibitors
Entry inhibitors
HSV keratitis topical drug?
Idoxuridine
DOC resistant herpes?
Foscarnet
Doc CMV retinitis
Oral valaganciclovir
Drugs not to be used with ganciclovir
Zidovudine, linezolid, anticancer drugs (Bone marrow suppression)
Doc recurrent laryngeal papillomatosis
Cidofovir i/v
Drug with multiple effects on electrolyte balance
Foscarnet
Drugs that prevent viral attachment & entry
Enfuvirtide, maraviroc, docosanol, palivizumab
Anti influenza drug used in Parkinsonism
Amantidine
Neuraminidase inhibitors
Oseltamivir, zanamivir
