Drug Of Choice Flashcards
(219 cards)
1
Q
Mucormycosis
A
Am-b
2
Q
Kala Azar
A
Am-b
3
Q
Systemic candida meningitis
A
Am-b
4
Q
Coccidioidal meningitis
A
Fluconazole
5
Q
Mucocutaneous candidiasis (albicans only)
A
Fluconazole
6
Q
Oral candidiasis
A
Topical clotrimazole
7
Q
Dermatophytes
A
Itraconazole I
8
Q
Sporotrichosis
A
Itraconazole
9
Q
Endemic mycoses
A
Itraconazole
10
Q
Invasive aspergillosis
A
Voriconazole
11
Q
Prophylaxis of invasive aspergillosis
A
Posaconazole
12
Q
Gvhd antifungal
A
_Posaconazole
13
Q
Tinea capitis
A
Griseofulvin
14
Q
Non albican candida
A
Echinocandins
15
Q
Onychomycosis
A
Oral terbinafine
16
Q
Doc partial seizure
A
Carbamazepine
17
Q
Absent seizures
A
Valproate
18
Q
GTCS
A
Valproate
19
Q
Atypical absent seizure
A
Valproate
20
Q
Doc liver toxicity & hyperammonemia
A
Carnitine
21
Q
Typical absent seizures
A
Ethosuximide
22
Q
Trigeminal neuralgia
A
Carbamazepine
23
Q
Infantile spasm with tuberous sclerosis
A
Vigabatrin
24
Q
DOC in infantile spasms without tuberous sclerosis
A
ACTH or steroids
25
Post herpetic neuralgia, DOC:
Gabapentin
26
Safest anti epileptic in pregnancy
Levertiracetam
27
Status epilepticus DOC
Lorazepam
28
DOC Febrile seizure with RoA
Rectal diazepam
29
Drug of choice for seizure in neonates
Phenobarbital
30
DOC Criggler Najar syndrome type 2
Phenobarbital
31
Sleep maintenance, drug of choice
DORA
32
DOC post anaesthetic chills
Pethidine/ Meperidine
33
DOC chills caused by monoclonal antibodies
Pethidine/ Meperidine
34
DOC non-secretory diarrhoea
Loperamide
35
Opioid toxicity drug of choice
Naloxone
36
Prophylaxis of mania drug of choice
Lithium
37
Drug of choice for bipolar disorder
Lithium
38
Drug of choice for acute mania
Lithium
39
Drug of choice for hypnic headache
Lithium
40
Lithium induced DI doc
Amiloride
41
Drug of choice for mania during pregnancy
Aripiprazole
42
Depression DOC
SSRI
43
Cheese reaction DOC
Phentolamine IV
alpha blocker
44
TCA toxicity DOC
Sodium bicarbonate
45
DOC PMS
SSRI
46
DOC neurosis
SSRI
47
DOC depression assoc w insomnia or erectile dysfunction
Mirtazapine / Mianserin
48
DOC morphine poisoning
Naloxone
49
DOC Resistant schizophrenia
Clozapine
50
DOC suicidal tendency in psychosis
Clozapine
Due to D4 block
51
DOC Levodopa induced psychosis
Pimavanserin
52
DOC akathisia
B#
53
DOC to overcome Parkinsonism
Anticholinergics- Benzhexol
Other: benztropine , biperiden
54
DOC Tardive dyskinesia
VMAT2 inhibitors like Valbenazine, deutetrabenazine
55
DOC for NMS (neuroleptic malignant syndrome)
Dantrolene
56
DOC Malignant hyperthermia
Dantrolene
57
DOC Alzheimer’s
Donepezil
58
DOC PD >65 years
Levodopa
59
DOC (?) levodopa induced dyskinesia
Amantidine > Leviteracetam
60
DOC on off phenomenon in PD
COMT inhibitors peripheral - Entacapone, Opicapone
61
DOC hyperprolactinemia in female planning for pregnancy
Bromocriptine
62
DOC hyperprolactinemia
Cabergoline
63
DOC restless leg syndrome
Non ergot alkaloids - pramipexole, ropinirole, rotigotine
64
DOC PD <65 years
Non ergot alkaloids
65
DOC obesity
Liraglutide
66
DOC DM type 2
Metformin
67
DOC prophylaxis of pre diabetes
Metformin
68
DOC acromegaly
Octreotide LAR or lanreotide
69
DOC secretory diarrhoea
Somatostatin analogues
70
DOC glucagonoma, VIPoma, GRFoma
Somatostatin analogues
71
DOC somatostatinomas
Somatostatin analogues (yep. I know.)
72
DOC Insulinoma
Diazoxide
73
DOC acute variceal bleed
Terlipressin
74
DOC prostate cancer
Goserelin
75
DOC replacement of glucocorticoids in Addison’s disease , congenital adrenal hyperplasia
Hydrocortisone
76
DOC post menopausal osteoporosis
Oral bisphosphonates
77
DOC hypercalcemia of malignancy
Bisphosphonates
78
DOC pagets disease
Bisphosphonates
79
Overall DOC for hyperthyroidism
Methimazole
80
DOC hypothyroidism in pregnancy 1st trimester
Propylthiouracil
81
DOC for hyperthyroidism in lactation
PTU
82
DOC for severe thyrotoxicosis
PTU
However, the first drug administered is propanolol to prevent arrhythmia
83
Drug of choice in surgical prophylaxis (anti bacterial)
Cefazolin
84
DOC Gonorrhea
Ceftriaxone
85
DOC meningitis except Listeria
Ceftriaxone
86
DOC pseudomonas
Ceftazidime
87
DOC meliodosis
Ceftazidime
88
DOC febrile neutropenia
Ceftazidime
89
DOC E.coli
Ceftriaxone
90
DOC Klebsiella
Ceftriaxone
91
DOC providencia
Ceftriaxone
92
Oral DOC typhoid
Cefixime
93
DOC ESBL
Imipenem + cilastatin
94
DOC serratia
Imipenem
95
DOC acinetobacter
Imipenem
96
DOC enterobacter
Imipenem
97
Close angle glaucoma drug of choice
Pilocarpine
98
Drug of choice for anticholinergic poisoning
Physostigmine
99
Drug of choice for Alzheimer’s disease
Donepezil
100
Drug of choice for Myasthenia gravis
Pyridostigmine
101
Drug of choice for treatment of myasthenic crisis
Intravenous immunoglobulin
102
Drug of choice for narco analysis
Thiopentone
103
Drug of choice for COPD (class)
Anti cholinergics
As the only reversible component of broncho constriction in COPD is the parasympathomimetic effect
104
Drug of choice class for bronchi asthma
Beta two agonists, because they are the physiological antagonist for histamine, which is responsible for broncho constriction
105
Drug of choice for motion sickness
Scopolamine
106
Drug of choice for steroid resistant nephrotic syndrome and ulcerative colitis
Cyclosporine
107
Drug of choice for early onset, nausea and vomiting in cancer chemotherapy
Ondansetron as it is short acting
108
Drug of choice for late onset, nausea and vomiting in cancer chemotherapy
Palonosetron or aprepitant
109
Overall drug of choice for nausea and vomiting and cancer chemotherapy
Ondansetron
110
Drug of choice for wegeners granulomatosis
Cyclophosphamide
111
Drug of choice for steroid dependent nephrotic syndrome
Cyclophosphamide
112
Drug of choice for steroid resistant nephrotic syndrome
Cyclosporin
113
Drug of choice for prevention of haemorrhagic cystitis in cyclophosphamide
Mesna at dose equal to 60% of the dose of cyclophosphamide administered
114
Regimen of choice for Hodgkin disease
ABVD
Adriamycin (doxorubicin)
Bleomycin
Vinblastine
Dacarbazine
115
Drug of choice for brain tumour
Temozolomide
116
Drug of choice for head and neck cancer
Cisplatin
117
Drug of choice for upper GIT cancer
Cisplatin
118
Drug of choice for gastric cancer
Cisplatin
119
Drug of choice for lower GIT cancer (colorectal and anal)
5fluorouracil
120
Drug of choice for urogenital cancer
Cisplatin
121
Drug of choice for osteosarcoma
Cisplatin
122
Drug of choice for lung carcinoma
Cisplatin
123
Treatment of choice for AML
Daunorubicin/ Idarubicin + cytarabine
124
Drug of choice for Kaposi sarcoma
Doxorubicin
125
Drug of choice for choriocarcinoma
Methotrexate
126
DOC carcinomatous meningistis
Methotrexate
127
Drug of choice for rheumatoid arthritis
Methotrexate
128
Drug of choice for psoriatic arthritis
Methotrexate
129
Drug of choice for histiocytosis
Vinblastine
130
DOC pancreatic cancer
Gemcitabine
131
Drug of choice for myelodysplasia
Azacytidine Decitabine
132
Drug of choice for prevention of tumour lysis syndrome
Allopurinol
133
Drug of choice for CLL
Fludarabine
134
Treatment of choice for CLL
FCR
fludarabine
Cyclophosphamide
Rituximab
135
Drug of choice for hairy cell leukaemia
Cladribine
136
Drug of choice for refractory histocytosis
Cladribine
137
Drug of choice for treatment of delayed diarrhoea due to irinotecan
Loperamide
138
Drug of choice for treatment of sickle cell anaemia
Hydroxyurea
139
Drug of choice for polycythaemia vera
Hydroxyurea
Newer drug anagrelide
140
Drug of choice for essential thrombocytemia
Hydroxyurea
141
Drug of choice for treatment of ER positive breast cancer in premenopausal females
Tamoxifen
142
Drug of choice for reflexes of ER positive breast carcinoma in premenopausal females
Tamoxifen
143
Drug of choice for Riedels thyroiditis
Tamoxifen
144
Drug of choice for treatment of Tamoxifen or Letrozole Resistant ER positive breast cancer in post menopausal , female
Fluvestrant
145
Drug of choice for treatment of ER positive breast cancer in post menopausal female
Letrozole
146
Drug of choice for infertility caused by anovulation
Aromatase inhibitors like Letrozole
147
DRug of choice for androgenic alopecia
Five. Alpha reductive inhibitors. Like finasteride and dutasteride
148
Drug of choice for multiple myeloma
Bortezomib
149
Drug of choice for HER2 positive breast cancer
Trastuzumab, Pertuzumab
150
DOC RCC
Bevacizumab or Sunitinib
151
DOC HCC
Sorafenib
152
DOC CML
Imatinib
153
Drug of choice for multi tyrosine kinase inhibitor resistant CML
Onacetaxine
154
DOC hypokalemic periodic paralysis
Methenamide
155
DOC acute mountain sickness
Oral Acetazolamide
156
DOC pulmonary edema
Loop diuretics
157
DOC cerebral edema
Mannitol
158
Drug of choice for hypertension with osteoporosis
Thiazides
159
Drug of choice for cirrhotic edema
Spironolactone
160
DOC resistant hypertension
Spironolactone
161
DOC resistant edema
Spironolactone
162
DOC Liddle syndrome
Amiloride
163
DOC lithium induced diabetes inspidus
Amiloride
164
DOC acute congestive glaucoma
Mannitol
165
DOC acute variceal bleeding
Terlipressin over octreotide
166
DOC Central DI
Desmopressin
167
DOC nocturnal enuresis
Desmopressin
168
DOC von willebrand disease
Desmopressin
169
DOC haemophilia A
Desmopressin
170
DOC Huntington chorea
Tetrabenazine & Deutetrabenazine
171
DOC for tardive dyskinesia
Deutetrabenazine and Valbenazine
172
DOC for cocaine dependence
Bromocriptine
173
DOC vasodilatory shock (sepsis)
Norepinephrine
174
DOC cardiogenic shock
NorEpinephrine
175
DOC cardiac arrest
Epinephrine (1:10,000)
176
DOC anaphylactic shock
Epinephrine 1:1000 IM
177
Inotrope of choice in acute CHF
Dobutamine
178
DOC priapism
Phenylephrine
179
DOC spinal anesthesia induced hypotension
Phenylephrine
Exception: if there is associated bradycardia then doc is ephedrine
180
DOC postural hypotension
Midodrine
181
DOC HTN urgency
Clonidine
182
DOC pregnancy induced HTN
Oral Labetolol
183
DOC ADHD
Methylphenidate
184
DOC ADHD with Tourette syndrome/family history of drug abuse
Atomoxetine
Viloxazine
185
DOC narcolepsy
Modafinil
186
DOC OSA, shift worker disease
Modafinil
187
DOC clonidine withdrawal hypertension
Phentolamine
188
DOC intraoperative HTN in pheochromocytoma
Phentolamine
189
DOC preoperative HTN in pheochromocytoma
Phenoxybenzamine
190
TOC in pheochromocytoma
Alpha blocker followed by beta blocker
191
DOC BPH+HTN
Alpha 1 blockers
Prazosin
192
DOC BPH ( no HTN)
Alpha 1A blocker
Tamsulosin
Silodosin
193
DOC scorpion bite
Prazosin
194
DOC migraine ppx
Beta blockers
195
DOC essential tremor
Beta blockers
196
DOC stable angina
Beta blockers
197
DOC hyperobstructive cardiomyopathy
Beta blockers
198
DOC aortic dissection
Beta blockers
199
Drug of choice for neurosurgery anaesthesia
Thiopentone sodium
200
Drug of choice for daycare anaesthesia
Propofol
201
Drug of choice for cardiac surgeries anaesthesia
Etomidate
202
DOC morning sickness
Doxylamine
203
DOC urticaria
Second generation antihistamines
204
DOC allergic rhinitis
Steroids
205
DOC hereditary angioedema treatment
C1 esterase inhibitors
206
DOC PPx of hereditary angioedema
Danazol
207
DOC migraine in pregnancy
Paracetamol
208
DOC cervical ripening
Dinoprostone
209
DOC open angle glaucoma
PGF 2Alpha analogs Latanoprost, Bimatoprost
210
DOC normal tension, glaucoma
PGF2 alpha analogues Latanoprost, Bimatoprost
211
DOC niacin induced flushing
Aspirin
212
DOC acute gout
Indomethacin
213
DOC paroxysmal hemicrania
Indomethacin
214
DOC closure of patent ductus arteriosus in India
Ibuprofen
215
DOC closure of patent ductus arteriosus international
Indomethacin
216
DOC, chronic gout
Allopurinol
217
DOC tumour lysis syndrome (high risk)
Rasburicase
218
DOC hyperuricemia in lesch nyhan syndrome
Allopurinol
219
DOC tumour lysis syndrome (low to moderate risk)
Allopurinol
