Antiviral Drugs Flashcards

(35 cards)

1
Q

The organism that can cause harmful infections.

A

Infectious Agent

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2
Q

Five (5) Infectious Agent

A
  1. Protozoa
  2. Fungi
  3. Bacteria
  4. Virus
  5. Parasitic Worms
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3
Q

Single-Celled. Unicellular parasites of the animal kingdom.

Ex: Malaria, Amoeba

A

Protozoa

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4
Q

Unicellular structures of the plant kingdom.

Ex: Athlete’s Foot (Tinea Pedis)

A

Fungi

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5
Q

Unicellular structures that reproduce sexually or asexually, grow on cell-free media, and can exist in an inanimate environment.

Ex: TB, Leprosy

A

Bacteria

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6
Q

Obligate intracellular parasites that are among the smallest of the biologic agents known to infect human. They consist of encapsulated genetic material.

Ex: COVID-19

A

Virus

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7
Q

Also known as “Helminths”

Cestodes, Trematodes, Nematodes

A

Parasitic Worms

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8
Q

Smallest of all the self replicating organisms.

A

Viruses

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9
Q

They utilize host metabolic enzymes and host ribosome for protein.

A

Parasitic

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10
Q

Surrounded by Protein

A

Capsid

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11
Q

Sometimes an Outer Lipid

A

Envelope

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12
Q

Complete Viral Particle

A

Virion

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13
Q

A single stranded RNA virus. Viral nucleic acids, is helical or tubular. The enveloped virions. A club-shaped glycoprotein spikes in the envelope give the viruses, crownlike or coronal appearance.

A

COVID-19

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14
Q

Six (6) DNA Viruses

A
  1. Herpesvirus
  2. Papovavirus
  3. Adenovirus
  4. Hepadnavirus
  5. Poxvirus
  6. Parvovirus
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15
Q

It is also known as “Kissing Disease”; This is one of the most common viruses in humans. It causes infectious mononucleosis. It is associated with cancers.

A

Epstein-Barr Virus

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16
Q

Seven (7) RNA Viruses

A
  1. Picornaviridae
  2. Togaviridae
  3. Paramyxoviridae
  4. Flaviviridae
  5. Reoviridae
  6. Orthomyxoviridae
  7. Rhabdoviridae
17
Q

It can infect the person’s spinal cord, causing paralysis (can’t move parts of the body).

A

Polio Virus (Poliomyelitis)

18
Q

It is also known as “German Measles”

A

Rubella Virus

19
Q

It is also known as “Koplik’s Spot”

A

Measles Virus / Rubeola (Tigdas)

20
Q

It is also known as “Break Bone Fever”

21
Q

It is known for “Stomach Flu”; The most common cause of severe diarrhea in infants and children.

22
Q

These are responsible for seasonal flu epidemics each year.

A

Influenza A and B

23
Q

A neurotropic virus that causes rabies in humans and animals.

A

Rhabdoviridae

24
Q

It weakens the person’s immune system by destroying important cells that fight disease and infection.

25
Two (2) Viral Enzymes
1. DNA Polymerases 2. RNA Polymerases
26
Two (2) DNA Polymerases
1. DNA-Dependent DNA Polymerase 2. RNA-Dependent DNA Polymerase
27
It is responsible for directing the synthesis of new DNA from deoxyribonucleotide triphosphates (dNTPs) opposite an existing DNA template, which contains the genetic information critical to an organism's survival.
DNA-Dependent DNA Polymerase
28
It is also known as "Reverse Transcriptase"; Initially isolated from retroviruses. A DNA polymerase enzyme that transcribes single-stranded RNA into DNA.
RNA-Dependent DNA Polymerase
29
Two (2) RNA Polymerases
1. RNA-Dependent RNA Polymerases 2. DNA-Dependent RNA Polymerases
30
An enzyme that catalyzes the replication of RNA from an RNA template. Specifically, it catalyzes synthesis of the RNA strand complementary to the given RNA template. RNA into RNA.
RNA-Dependent RNA Polymerases
31
It catalyze the cleavage of specific peptide bonds in viral polyprotein precursors or in cellular proteins.
Viral Proteases
32
A viral enzyme that catalyzes the integration of virally derived DNA into the host cell DNA in the nucleus.
Integrase
33
It occurs both influenza A and B virus. Responsible for cleaving the receptor to allow virus release.
Neuraminidase
34
It happens during viral replication. During the said process, viral genes undergo random "copying errors" (i.e., genetic mutations).
Viral Mutation
35
It is also known as "Antigenic Drift"
Antigens