aortic regurgitation Flashcards

1
Q

epidemiology

A

much less common than aortic stenosis or mitral valve disease

usually only trace or mild

incidence increases w/ age

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2
Q

Causes

A
  1. insufficiency of congenitally anomalous bicuspid valve
  2. endocarditis
  3. chronic rheumatic valve deformation
  4. dilation of aortic valve ring by aortic aneurysm or dissection
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3
Q

if half of pt’s SV is falling back into LV and pt can only compensate by increasing SV 20%, to 120mL…

How much is pumped into the aorta?

A

60mL pumped out

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4
Q

if half of pt’s SV is falling back into LV and pt can only compensate by increasing SV 20%, to 120mL..

What volume is left from last systole?

A

50mL

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5
Q

if half of pt’s SV is falling back into LV and pt can only compensate by increasing SV 20%, to 120mL…

How much fluid falls back into left ventricle?

A

60mL

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6
Q

if half of pt’s SV is falling back into LV and pt can only compensate by increasing SV 20%, to 120mL…

what volume is from the left atrium?

A

60mL

decreased from the normal 100mL b/c venous return is decreased

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7
Q

if half of pt’s SV is falling back into LV and pt can only compensate by increasing SV 20%, to 120mL…

What would the End-Diastolic Pressure be (if situation is acute?)?

A

around 50mmHg

Higher than the normal 10mmHg

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8
Q

if half of pt’s SV is falling back into LV and pt can only compensate by increasing SV 20%, to 120mL…

What would the End-diastolic volume be?

A

170 mL

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9
Q

Consequences of acute

A

increased LV diastolic pressure (hasn’t had time to dilate and accommodate)

  • ->increased left atrial pressure
  • ->pulmonary congestion and edema
  • ->dyspnea
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10
Q

Treatment of severe acute AR

A

surgical valve replacement (surgical emergency)

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11
Q

Chronic AR consequences

A

dilation of LV w/ increased muscle mass
–>inccreased compliance and less elevated LV diastolic pressure

pt. may be able to double SV to compensate for half of SV falling back into ventricle

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12
Q

chronic compensated aortic regurgitation:

If SV is 200mL…
What volume is pumped into aorta?

A

100mL

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13
Q

chronic compensated aortic regurgitation:

If SV is 200mL…
normal amount left in LV at end of systole

A

50mL

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14
Q

chronic compensated aortic regurgitation:

If SV is 200mL…
volume from left atrium?

A

100mL

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15
Q

chronic compensated aortic regurgitation:

If SV is 200mL…
volume that falls back into LV from aorta?

A

100mL

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16
Q

chronic compensated aortic regurgitation:

If SV is 200mL…
EDV?

A

250mL

17
Q

chronic compensated aortic regurgitation:

If SV is 200mL…
End diastolic pressure?

A

about 12mmHg

18
Q

chronic compensated aortic regurgitation:

If SV is 200mL…ejection fraction?

A

80%

SV/EDV

19
Q

How can chronic AR become decompensated?

A

diastolic BP falls b/c of blood leaking backward…
–heart gets coronary blood supply during diastole via coronary ostia just above aortic valve…
if coronary perfusion lowered sufficiently

–>decompensation

20
Q

Decompensation of chronic AR…

A

heart might only be able to pump out 150mL SV instead of 200.
If pt still losing half of SV back into ventricle, forward SV is then only 75mL (REMEMBER: clinical manifestations of HF)

may lead to:

  • -if pt retains enough fluid, addition of LA volume to LV EDV might increase from 100 to 175mL…yielding LV EDV of 300mL
  • ->and ED pressure of 25mmHg
21
Q

Symptoms of decompensated aortic regurgitation

A

fatigue
decreased exercise tolerance
dyspnea

22
Q

Signs of decompensated AR

A

diastolic decrescendo murmur (sometimes w/ a blowing quality)

hyperdynamic bounding

rapidly collapsing pulse (Corrigan pulse)

head-bobbing w/ eauch pulse (de Musset sign)

multiple other eponymic signs

23
Q

characteristic of aortic regurgitation

A

wide pulse pressure due to increased systolic and decreased diastolic pressure from the abnormally large amount of blood ejected into aorta in systole and back leak into LV in diastole

24
Q

Treatment of choice for symptomatic AR

A

aortic valve replacement