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ASA (Aspirin): Classification

1. Antiplatelet

2. Antithrombotic

3. Aspirin falls under many other functional classifications


ASA (Aspirin): Pharmacodynamic

1. Inhibits the formation of thromboxane A2 which is a potent platelet aggregate and vasoconstrictor


ASA (Aspirin): Pharmacokinetics

1. Intravenous
- Onset: 15 to 30 minutes
- Peak: 1 to 2 hours
- Duration: 4 to 6 hours


ASA (Aspirin): Indications

1. Chest pain or atypical symptoms consistent with cardiac ischemia/AMI


ASA (Aspirin): Contraindications

1. Allergy to aspirin or other non-steroidal anti-inflammatory (NSAIDS) agents. This includes man non-aspirin/non-Tylenol pain relievers such as Advil

2. Asthma (see special notes)

3. Recent head injury, stroke or acute bleeding (significant) of any kind

4. Paediatric patients with viral symptoms


ASA (Aspirin): Precautions

1. Recent internal bleeding (witching last 3 months)

2. Known bleeding diseases

3. Patients currently taking anticoagulant agent(s)

4. Recent surgery

5. Possibility of pregnancy


ASA (Aspirin): Dosage

1. 160 mg

2. Have the patient chew ASA before swallowing


ASA (Aspirin): Pediatric

1. Contraindicated in pediatric patients with viral illness

2. Chest pain in children is unlikely to be ischemic in nature therefore ASA not indicated unless rare specific ischemic cardiac history


ASA (Aspirin): Special Notes

1. ASA has been linked to Reye’s syndrome in children with a viral history such as chicken pox, or influenza

2. Asthma - contraindicated in patients who have experienced and exacerbation of their asthma after taking ASA