Associations (Diseases, Pathologies, Keywords) Flashcards Preview

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Flashcards in Associations (Diseases, Pathologies, Keywords) Deck (151):
1

Abetalipoproteinemia

Acanthocyte

2

Visceral malignancy; also seen in DM

Acanthosis nigricans

3

APKD1; flank pain, hematuria, HTN, UTI, renal failure; polycystic liver disease, berry aneurysms, MVP

Adult Polycystic Kidney Disease

4

Guillain-Barre syndrome

Albuminocytologic dissociation

5

TdT+; children

ALL

6

Auer rods; adults

AML

7

M3; t(15;17); tx with Retinoic acid

AML with DIC

8

M5 (

AML with gingival hyperplasia

9

A_ (A4) amyloid fibrils,

Alzheimer�s disease

10

Leishmaniasis (Tx: sodium stibogluconate)

Amastigotes

11

AL protein

Amyloidosis, primary

12

Amebic liver abscess

Anchovy paste aspirate

13

Polyvinyl chloride

Angiosarcoma of the liver

14

HLA-B27, Marie-Strumpell disease, bamboo spine

Ankylosing spondylisis

15

Coal-worker pneuomoconiosis

Anthracosis

16

CREST syndrome

Anticentromere antibody

17

Pemphigus vulgaris (deadly)

Antidesmosome IgG

18

Bullous pemphigoid (spares oral mucosa)

Antihemidesmosome IgG

19

Water-hammer pulse, Corrigan�s pulse; Quincke�s sign; DeMusset�s sign; Duroziez�s sign; Traube�s sign; Austin-Flint murmur; Hill�s sign; Muller sign, Bisferiens pulse

Aortic Regurgitation

20

Gallavardin�s phenomenon, soft S2, S4, forceful apex

Aortic stenosis

21

Colorectal CA

�Apple core� on abdominal Xray

22

Tuberous sclerosis

Ash-leaf spot

23

Chlamydia, Mycoplasma, Legionella, viral

Atypical pneumonia

24

AML M3 (Acute promyelocytic leukemia)

Auer rods

25

Palisading nuclei, pearly papules, �rodent ulcer�

Basal Cell CA

26

Achalasia

�Bird-beak� X-ray

27

G6PD Deficiency

Bite cell

28

Dubin-Johnson syndrome

Black liver

29

Congenital rubella

�Blueberry Muffin� rash

30

RHD pericarditis

�Bread and butter� pericardium

31

Chordoma

�Bubble-bearing� cells

32

TTP, HUS

Burr cell

33

Glioblastoma multiforme

�Butterfly glioma�

34

Urinary 5-HIAA; wheezing, R-sided murmurs, diarrhea, flushing

Carcinoid syndrome

35

Distended bladder, flaccid rectal sphincter, perineal saddle anesthesia

Cauda equina syndrome

36

Antigliadin antibodies, B12 deficiency, dermatitis herpetiformis

Celiac disease

37

Headache, tinnitus, thrombocytopenia

Cinchonism

38

Avascular necrosis of femoral head

�Crescent sign� on X-ray

39

Taenia solium

Cysticercosis

40

Heliotrope rash, �shawl and face� rash, �risk of malignancy, � CK, � aldolase, (+) ANA, (+) anti-Jo-1

Dermatomyositis

41

Clear cell vaginal CA (in daughters)

DES exposure

42

Fascial soft tissue neoplasm, probably fibrosarcoma, tx wide excision with 2-4cm margin

Desmoid tumor

43

� width of GBM, Kimmelstein-Wilson lesions, necrobiosis lipoidica (shins), Armanni-Ebstein lesion

Diabetes Mellitus

44

ALL, AML; endocardial cushion defects

Down syndrome

45

Mulberry nodules, chocolate cysts, gunpowder-mark lesions

Endometriosis

46

Osteopetrosis

�Erlenmeyer flask� bones

47

Lyme disease

Erythema migrans (with target lesions)

48

In G6PD deficiency, hemolysis post-fava bean ingestion

Favism

49

Sickle cell anemia

Fish mouth vertebra

50

Malignant hypertension

Flea-bitten kidney

51

Oligodendroglioma, Multiple myeloma, Seminoma

�Fried egg� appearance

52

AdenoCA, Krukenberg tumors, Virchow�s node, linitis plastic, type A blood, liver mets, signet ring, acanthosis nigricans

Gastric CA

53

[arise from] Interstitial cell of Cajal

Gastrointestinal stromal tumor (GIST)

54

Necrolytic migratory erythema

Glucagonoma

55

Hepatitis B

�Ground glass� hepatocytes

56

Pneumocystis pneumonia or ARDS

�Ground glass� CXR

57

TRAP (Tartrate-resistant acid phosphatase); splenomegaly (80%)

Hairy Cell Leukemia

58

Alcoholic cirrhosis

�Hobnail� liver

59

Idiopathic pulmonary fibrosis

Honeycomb lung

60

Heart failure cells (intraalveolar hemosiderin-laden macrophages); brown induration

Heart failure, left-sided

61

Nutmeg liver

Heart failure, right-sided

62

Thalassemia, Anemia of chronic disease, Iron deficiency, Lead poisoning (TAIL)

Helmet cell

63

Cirrhosis, DM, increased skin pigmentation

Hereditary hemochromatosis

64

Spectrin, ankyrin, band 3, protein 4.2 deficiency

Hereditary spherocytosis

65

Vitamin B12/Folate deficiency

Hypersegmented neutrophils

66

Slipped capital femoral epiphysis

�Ice cream cone� hip

67

Roth spots, splinter hemorrhages, Osler�s (painful, pads of fingers)), Janeway (painless, palms and soles)

Infective Endocarditis

68

Erythema multiforme minor

Iris/target lesions [derma]

69

Linitis plastica, diffusely infiltrative gastric CA

Leather bottle stomach

70

Flea-bitten kidney, �onion-skin�

Malignant hypertension

71

P. falciparum

Malignant malaria

72

Asbestosis

Malignant mesothelioma

73

Babesiosis

�Maltese cross� inclusions

74

�Coast of Maine� lesions, short stature, precocious puberty

McCune-Albright syndrome

75

Cystic fibrosis

Meconium ileus

76

Hyperphosphatemia

Metastatic calcification

77

Anti-nRNP/Anti-U1RNP; Raynaud�s arthralgia, esophageal hypomotility

Mixed Connective Tissue Disease

78

Acute tubular necrosis

�Muddy brown� casts

79

Punched-out lesions, Bence-Jones protein, rouleaux formation, �fried-egg� plasma cells

Multiple Myeloma

80

Demyelination scattered about CNS white matter; internuclear ophthalmoplegia (MLF syndrome)

Multiple sclerosis

81

Neonatal hypersecretion of insulin; requires 95% pancreatectomy

Nesidioblastosis

82

Homer-Wright pseudorosettes, opsoclonus (dancing eyes), most common solid tumor in children, n-myc

Neuroblastoma

83

Noncaseating granuloma; Schaumann bodies; asteroid bodies; type IV reaction; Lupus pernio (violaceous, nose and ears)

Sarcoidosis

84

Anti-Scl-70 (in diffuse scleroderma)

Scleroderma

85

Giant cell tumor

Soap bubble appearance

86

Diabetes, steatorrhea, gallstones

Somatostatinoma

87

Cushing�s syndrome

Oat Cell Carcinoma

88

Ewing sarcoma

�Onion skin� pattern on X-ray

89

Primary sclerosing cholangitis

�Onion skin� bile duct

90

Eburnation, Heberden�s (DIP), Bouchard�s (PIP)

Osteoarthritis

91

Codman triangle, sunburst pattern

Osteosarcoma

92

Idiopathic crescentic GN, Churg-Strauss, Microscopic polyangitis, polyarteritis nodosa

P-ANCA

93

Scarlet fever

Pastia�s lines

94

Basal Cell CA

Pearly translucent papule with telangiectasia

95

Psoriatic arhtritis

�Pencil and cup� deformity

96

5_-reductase deficiency

�Penis at 12�

97

Urine metanephrine (most specific) or VMA; secretes NE extra-adrenally; Epi adrenally

Pheochromocytoma

98

Rosenthal fibers; common in children

Pilocytic astrocytoma

99

PTB

Pleural adenosine deaminase (increased)

100

CD8 T-cell induced muscle injury; progressive symmetric proximal weakness; anti-Jo-1

Polymyositis

101

Gliobastoma multiforme

Pseudopalisade

102

Hampton�s hump, Westermark�s sign; triad: hemoptysis, dyspnea, chest pain

Pulmonary embolism

103

Graham Steell murmur

Pulmonic Regurgitation

104

Takayasu�s arteritis

Pulseless disease

105

Hematuria, flank pain, flank mass

Renal Cell CA

106

Aschoff bodies (classic), Anitschkow�s cells (pathognomonic), MacCallum plaque, Sydenham�s chorea

Rheumatic Heart Disease

107

Rachitic rosary (also in scurvy), Harrison groove, pigeon breast, short stature, craniotabes, late fontanelle closure

Rickets

108

Basal cell CA

�Rodent ulcer�

109

Malignant Melanoma

S-100 tumor marker

110

Secondary amyloidosis

Sago spleen

111

�Pasted on� lesions; horn cysts, older persons

Seborrheic keratosis

112

�Crew cut� x-ray, missense mutation (Glu�Val), Salmonella osteomyelitis, malaria-resistant

Sickle-cell anemia

113

Krukenberg tumor, Gastric CA

Signet-ring cells

114

Birefringent silica particles

Silicosis

115

Anti-SS-A (Ro), Anti-SS-B (La)

Sjogren�s syndrome

116

ANA (sensitive but not specific, anti-dsDNA (specific and prognostic), anti-Sm (specific but not prognostic)

SLE

117

SIADH

Small cell carcinoma

118

CLL

Smudge cells

119

TAPVR

�Snowman� heart

120

Cryptococcus meningitis

�Soap bubble� lesion in brain

121

Membranous GN

�Spike and dome� appearance

122

Chronic constrictive pericarditis

�Square root sign� [equalization of pressures]

123

Burkitt�s lymphoma

Starry-sky appearance

124

SBO

Stepladder appearance

125

Trichomoniasis

Strawberry cervix

126

Cholesterolosis

Strawberry gallbladder

127

Scarlet fever, Kawasaki disease

Strawberry tongue

128

Crohn Disease

�String� sign in terminal ileum

129

Urease-positive bugs (Proteus, Klebsiella, Staph, Providencia, Pseudomonas); staghorn calculus

Struvite (Mg Ammonium Phosphate) stones

130

Osteosarcoma

�Sunburst� pattern

131

Cysticercosis

�Swiss Cheese� brain

132

Anti-Scl-70

Systemic Sclerosis

133

HbC disease, Asplenia, Liver disease, Thalassemia (HALT)

Target cell

134

Erythema multiforme, Lyme disease

Target lesions

135

Chronic idiopathic myelofibrosis / Myeloid metaplasia

Teardrop-shaped erythrocytes

136

Epiglottitis

Thumb sign

137

Struma ovarii

Thyroid tissue in ovary

138

Pyelonephritis

Thyroidization of kidney

139

Chlamydia trachomatis (A-C)

Trachoma

140

Membranoproliferative GN

Tram-track appearance

141

_-naphthalene exposure

Transitional cell CA

142

Syphilitic aortitis

Tree-bark aorta

143

Tumbling motility, strawberry cervix

Trichomonas vaginalis

144

Fever, purpura, hemolytic anemia, hematuria, neurologic changes

TTP pentad

145

Ash-leaf spot, Shagreen�s area, Koenen�s tumor

Tuberous sclerosis

146

Gastric antral vascular ectasia (Tx: antrectomy)

Watermelon stomach

147

C-ANCA

Wegener�s granulomatosis

148

Pyelonephritis (pathognomonic)

White cell casts

149

Type IV Lupus nephropathy (diffuse proliferative)

Wire-loop abnormality

150

Schiller-Duval bodies

Yolk sac tumor

151

Schwannoma

�Zebra stripes� neural tumor