Pharma- indications and MOA Flashcards Preview

PBR Fast Review by Cliff > Pharma- indications and MOA > Flashcards

Flashcards in Pharma- indications and MOA Deck (54):
1

Active against PRSPs

Ceftriaxone, cefotaxime

2

ADH antagonist tetracycline

Demeclocycline

3

AML M3 treatment

Retinoic acid

4

Anaerobes above the diaphragm

Clindamycin (static, 50S)

5

Anaerobes below the diaphragm

Metronidazole (disulfiram rxn, metallic taste)

6

Anti-liver schizonts

Primaquine

7

Anti-sense DNA (for CMV)

Fomivirsin

8

Atypical antipsychotic

Clozapine (D4 and 5-HT2 selective), Olanzapine (5-HT2)

9

AV nodal arrhythmias

Adenosine

10

Biliary excretion (beta-lactams)

Cefoperazone, Ceftriaxone, Nafcillin

11

Cestodes

Praziquantel and niclosamide

12

Chagas disease

Nifurtimox

13

Chronic heart failure

Labetalol, carvedilol, metoprolol

14

Chronic Myelogenous Leukemia

Imatinib (Gleevec)

15

Claudication

Cilostazol

16

CMV retinitis

Ganciclovir

17

Cysticercosis

Albendazole, praziquantel

18

Decreases post-op ileus

Erythromycin, Ketorolac

19

Depletes magnesium

Amphotericin, AGs, Foscarnet, Cisplatin, Ifosfamide

20

Derma steroid of choice (oral)

Prednisone

21

Not dialyzable

Amphotericin B, cefonicid, cefoperazone, ceftriaxone, erythromycin, nafcillin, tetracycline, vancomycin

22

Disulfiram-like reaction

Metronidazole, TMP-SMX, cefotetan, cefoperazone, cefamandone, 1st-gen sulfonylureas

23

Dissociative anesthesia

Ketamine

24

Elective bowel surgery

Neomycin and erythromycin

25

Eschar treatment

Mafenide acetate

26

Exacerbate psoriasis

Beta-blockers, lithium, ACE inhibitors

27

Gynecomastia

Spironolactone, Digitalis, Cimetidine, Alcohol, Ketoconazole, Furosemide, Diazepam, Verapamil, MJ

28

Hydatid disease

Albendazole

29

Iodine-containing antiarrhythmic

Amiodarone

30

Increase insulin secretion

B2 agonists

31

Increase renin secretion

B1 agonists

32

Leishmaniasis

Sodium stibogluconate

33

Longest-acting B-blocker

Nadolol

34

Mast cell degranulation blocker

Cromolyn sodium

35

Mountain sickness

Acetazolamide

36

Myasthenia gravis diagnosis

Edrophonium

37

Nephrotoxic agent used in surgery

Furosemide (also AGs, vanco)

38

Neutropenic nadir post-chemotherapy

7-10 days

39

Onchocerciasis (river blindness)

Ivermectin

40

Opioid with minimal histamine release

Fentanyl, remifentanil

41

Parenteral NSAID

Ketorolac

42

Partial _-agonists

Labetalol, pindolol, acebutolol

43

Pneumocystis pneumonia

TMP-SMX

44

Poxvirus inhibitor

Methisazone

45

Quinine-resistant malaria

Artemesins (artesunate, artemether)

46

[Most] S phase specific antimetabolite

Cytarabine

47

Sildenafil interaction

Nitrates (may cause hypotension)

48

�Stage-fright�

Propranolol

49

Tamoxifen optimum treatment time

5 years

50

TCA with H1/H2 blocking actions

Doxepin

51

Thrombolytic toxicity (antidote)

Aminocaproic acid

52

Topical steroid for face and intertriginous areas

Hydrocortisone acetate (low-potency)

53

Urge incontinence

Oxybutyrin, metaproterenol

54

Wolff-Parkinson-White syndrome

Amiodarone, Flecainide