Pharma- Associations, Drugs and Toxicities 2

Question 1

ACE inhibitors

Answer 1

Hyperkalemia, taste changes, cough, angioedema

Question 2

Alpha-blockers

Answer 2

Orthostatic hypotension, reflex tachycardia (nonselective)

Question 3

Amiodarone

Answer 3

Pulmonary fibrosis, hepatotoxicity, hyper/hypothyroid, corneal deposits, photodermatitis

Question 4

Ampicillin

Answer 4

Non-allergic maculopapular rash

Question 5

Angiotensin antagonists

Answer 5

Hyperkalemia

Question 6

Antiarrhythmics (Class I)

Answer 6

Hyperkalemia

Question 7

Atypical antipsychotics

Answer 7

Weight gain, type 2 DM, QT prolongation

Question 8

Clozapine

Answer 8

Agranulocytosis

Question 9

Diazoxide

Answer 9

Hypoglycemia

Question 10

Digitalis

Answer 10

ﾇPR, ﾉQT, ST scooping, T-wave inversion, yellow vision, arrhythmia, ﾇparasympathetic

Question 11

Heparin

Answer 11

Osteoporosis; thrombocytopenia

Question 12

Hydralazine

Answer 12

SLE-like syndrome, reflex tachycardia

Question 13

Mecasermin (GH-IGF binding protein-3)

Answer 13

Hypoglycemia

Question 14

Metformin

Answer 14

Lactic acidosis

Question 15

Methicillin

Answer 15

Interstitial nephritis

Question 16

Methyldopa

Answer 16

Hemolytic anemia

Question 17

Metoprolol

Answer 17

Dyslipidemia

Question 18

Minoxidil

Answer 18

Pericardial effusion, hypertrichosis

Question 19

Nucleoside inhibitors

Answer 19

Myelosuppression, ancreatitis, peripheral neuropathy

Question 20

Prilocaine

Answer 20

Methemoglobinemia

Question 21

Sulfasalazine

Answer 21

Reversible oligospermia, sulfonamide toxicity

Question 22

Tamoxifen

Answer 22

ﾇEndometrial CA, hot flushes, ﾇ DVT